Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.52 |
| ▸ | PLD1 | Q13393 | 13/20 | 0.50 |
| ▸ | PLD2 | O14939 | 12/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | YEATS4 | O95619 | 1/20 | 0.45 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.45 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | YEATS2 | Q9ULM3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439022 | 0.88 | PLD2 (0.55) | OPRM1PLD1PLD2DRD2HTR1A | |
| SCHEMBL4438708 | 0.85 | PLD1 (0.48) | OPRM1PLD1PLD2DRD2HTR1A | |
| SCHEMBL4434580 | 0.84 | PLD2 (0.47) | OPRM1PLD1PLD2DRD2KCNH2 | |
| SCHEMBL4439185 | 0.83 | PLD2 (0.56) | OPRM1PLD1PLD2DRD2HTR1A | |
| SCHEMBL4440705 | 0.83 | YEATS4 (0.65) | OPRM1PLD1PLD2DRD2HTR1A | |
| SCHEMBL5000658 | 0.83 | PLD1 (0.47) | OPRM1PLD1PLD2DRD2HTR1A | |
| SCHEMBL4436944 | 0.82 | PLD2 (0.47) | PLD1PLD2DRD2HTR1AADRA2A | |
| SCHEMBL4437904 | 0.82 | PLD2 (0.43) | OPRM1PLD1PLD2DRD2YEATS4 | |
| Hydrochloric Acid SCHEMBL4554319 | 0.82 | PLD2 (0.47) | PLD1PLD2DRD2HTR1AADRA2A | |
| SCHEMBL4434535 | 0.81 | PLD2 (0.45) | OPRM1PLD1PLD2DRD2YEATS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287479-A1 | INHIBITORS OF SERINE PALMITOYLTRANSFERASE | PFIZER INC | 2008-11-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287479-A1 | INHIBITORS OF SERINE PALMITOYLTRANSFERASE | SPTLC1, SPTLC2, CPT1A | OPRM1 4069/4885PLD1 351/4885PLD2 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.