Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.34 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | NEK2 | P51955 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5001639 | 1.00 | ERN1 (0.44) | ERN1ALDH1A1EGFRRETKDM4E | |
| SCHEMBL5216253 | 0.92 | CYP2A6 (0.44) | ERN1ALDH1A1KDM4ECYP2A6MAPT | |
| SCHEMBL5216249 | 0.92 | CYP2A6 (0.44) | ERN1ALDH1A1KDM4ECYP2A6MAPT | |
| SCHEMBL8362192 | 0.83 | ERN1 (0.53) | ERN1ALDH1A1PDCD1CD274CYP2A6 | |
| SCHEMBL4998563 | 0.81 | NAAA (0.47) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL4998558 | 0.81 | NAAA (0.47) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL4994349 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL4994355 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL3146081 | 0.78 | ALDH1A1 (0.52) | ERN1ALDH1A1PDCD1CD274CYP2A6 | |
| SCHEMBL14216188 | 0.78 | ERN1 (0.43) | ERN1ALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119499-A1 | Compositions Havinge Improved 2-Photon Absorbance For Nonlinear Applications | MEMPILE INC. (DE) | 2008-05-22 | — | — | US | claimed |
| US-20080119499-A1 | Compositions Havinge Improved 2-Photon Absorbance For Nonlinear Applications | MEMPILE INC. (DE) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119499-A1 | Compositions Havinge Improved 2-Photon Absorbance For Nonlinear Applications | HTR3D, CRY2, CNDP2 | ERN1 4268/4885ALDH1A1 281/4885EGFR 3832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.