Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 6/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2584537 | 0.90 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EGAAPKM | |
| SCHEMBL2588065 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EGAAPKM | |
| SCHEMBL2578532 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EGAAPKM | |
| SCHEMBL2587761 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EGAAPKM | |
| SCHEMBL28523812 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4EGAAPKM | |
| SCHEMBL28523811 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4EGAAPKM | |
| SCHEMBL2346620 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EGAAPKM | |
| SCHEMBL2346622 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EGAAPKM | |
| SCHEMBL2587430 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EGAAPKM | |
| SCHEMBL28907996 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207900-A1 | TWO CYCLIC OXOMORPHORIN DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207900-A1 | TWO CYCLIC OXOMORPHORIN DERIVATIVES | OPRM1, OPRK1, OPRD1 | ALDH1A1 2062/4885MAPT 3723/4885KDM4E 4439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.