Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28777083 | 0.98 | TSHR (0.40) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL18902603 | 0.81 | TSHR (0.39) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL15184059 | 0.78 | NPSR1 (0.37) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL29074516 | 0.76 | NR4A1 (0.47) | TSHRALDH1A1TDP1MAPK1L3MBTL1 | |
| SCHEMBL941751 | 0.76 | ALDH1A1 (0.40) | TSHRALDH1A1HSD17B10MAPK1PTGS2 | |
| SCHEMBL742856 | 0.75 | ALDH1A1 (0.39) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL3838039 | 0.74 | ALDH1A1 (0.45) | TSHRALDH1A1L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL16729686 | 0.73 | NPC1 (0.51) | ALDH1A1MAPTGAAMEN1MITF | |
| SCHEMBL633340 | 0.73 | CFTR (0.34) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL4166448 | 0.72 | CA2 (0.47) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2861559-B1 | METHOD AND CATALYST FOR SYNTHESISING AZIRIDINE | UNIV OF EAST ANGLIA (GB) | 2020-09-16 | — | — | EP | disclosed |
| US-10259784-B2 | Method and catalyst for synthesising aziridine | UNIVERSITY OF EAST ANGLIA (GB) | 2019-04-16 | — | — | US | disclosed |
| US-9919300-B2 | 1-hexene production process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-03-20 | — | — | US | disclosed |
| US-20170342030-A1 | METHOD AND CATALYST FOR SYNTHESISING AZIRIDINE | UNIV OF EAST ANGLIA (GB) | 2017-11-30 | — | — | US | disclosed |
| EP-2484685-B1 | TRANSITION METAL COMPLEX, PREPARATION METHOD FOR SAID TRANSITION METAL COMPLEX, TRIMERIZATION CATALYST, PREPARATION METHOD FOR 1-HEXENE, PREPARATION METHOD FOR ETHYLENE POLYMER, SUBSTITUTED CYCLOPENTADIENE COMPOUND, AND PREPARATION METHOD FOR SAID SUBSTITUTED CYCLOPENTADIENE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2017-11-01 | — | — | EP | disclosed |
| US-9732034-B2 | Method and catalyst for synthesising aziridine | UNIVERSITY OF EAST ANGLIA (GB) | 2017-08-15 | — | — | US | disclosed |
| US-20170152225-A9 | METHOD AND CATALYST FOR SYNTHESISING AZIRIDINE | UNIVERSITY OF EAST ANGLIA (GB) | 2017-06-01 | — | — | US | disclosed |
| US-20170036200-A1 | 1-HEXENE PRODUCTION PROCESS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-09 | — | — | US | disclosed |
| EP-2356517-B1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND PATTERN FORMING METHOD USING THE SAME | FUJIFILM CORP (JP) | 2017-01-25 | — | — | EP | disclosed |
| US-9090527-B2 | Method for producing transition metal complex, catalyst for trimerization, method for producing 1-hexene, method for producing substituted cyclopentadiene compound (2) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-07-28 | — | — | US | disclosed |
| EP-0810864-A1 | 2,6-DIARYL PYRIDAZINONES WITH IMMUNOSUPPRESSANT ACTIVITY | Merck & Co., Inc. (US) | 1997-12-10 | — | — | EP | disclosed |
| US-5670504-A | 2,6-diaryl pyridazinones with immunosuppressant activity | MERCK & CO. INC. (US) | 1997-09-23 | — | — | US | disclosed |
| WO-1996025936-A1 | 2,6-DIARYL PYRIDAZINONES WITH IMMUNOSUPPRESSANT ACTIVITY | MERCK & CO., INC. (US) | 1996-08-29 | — | — | WO | disclosed |
| US-4740610-A | Process for the preparation of N,o-substituted mono- and/or polyurethanes | BASF AKTIENGESELLSCHAFT (DE) | 1988-04-26 | — | — | US | disclosed |
| US-4695645-A | Process for the preparation of N,o-substituted mono-and/or polyurethanes | BASF AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | disclosed |
| US-4552586-A | Certain 2-pyridyloxyacetanilides and their use as herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-11-12 | — | — | US | disclosed |
| EP-0078005-B1 | METHOD FOR THE PREPARATION OF ISOCYANATES BY PYROLYSIS OF URETHANES | BASF Aktiengesellschaft (DE) | 1985-08-07 | — | — | EP | disclosed |
| US-4530796-A | Vapor phase pyrolysis | BASF AKTIENGESELLSCHAFT (DE) | 1985-07-23 | — | — | US | disclosed |
| EP-0133274-A1 | Process for the preparation of N,0-substituted mono- and/or polyurethanes | BASF Aktiengesellschaft (DE) | 1985-02-20 | — | — | EP | disclosed |
| US-4423247-A | AMINOALKYLATION, NONCATALYTIC REACTION | BASF AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170036200-A1 | 1-HEXENE PRODUCTION PROCESS | AP1M1, HK1, CYC1 | TSHR 1183/4885ALDH1A1 1321/4885TDP1 1578/4885 |
| US-10259784-B2 | Method and catalyst for synthesising aziridine | ITPA, PPA1, PPIP5K2 | TSHR 1511/4885ALDH1A1 2657/4885TDP1 2265/4885 |
| US-20170342030-A1 | METHOD AND CATALYST FOR SYNTHESISING AZIRIDINE | ITPA, PPA1, PPIP5K2 | TSHR 1511/4885ALDH1A1 2657/4885TDP1 2265/4885 |
| US-20170152225-A9 | METHOD AND CATALYST FOR SYNTHESISING AZIRIDINE | ITPA, PPA1, PPIP5K2 | TSHR 1503/4885ALDH1A1 2656/4885TDP1 2500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.