SCHEMBL5003363

SCHEMBL5003363

C[SiH](C)[Zr](Cl)(Cl)(C1c2cc(Br)ccc2-c2ccc(Br)cc21)C1c2cc(Br)ccc2-c2ccc(Br)cc21

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.32
S100A4 P26447 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5009172 0.92 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3
SCHEMBL2485514 0.76 ALDH1A1 (0.31)
SCHEMBL5006909 0.73 S100A4 (0.35) S100A4SLC6A2SLC6A4SLC6A3
SCHEMBL3644683 0.73 SLC22A2 (0.39) SLC6A2SLC6A4SLC6A3
SCHEMBL4999960 0.72 SLC22A2 (0.31)
Hydrochloric Acid SCHEMBL5003364 0.70 PGR (0.33) PGRS100A4SLC6A2SLC6A4SLC6A3
SCHEMBL5003677 0.69 SLC6A2 (0.41) PGRSLC6A2SLC6A4SLC6A3
SCHEMBL5129021 0.69 CYP1A2 (0.39) SLC6A2SLC6A4SLC6A3
SCHEMBL13995259 0.68 PGR (0.41) PGRS100A4SLC6A2SLC6A4SLC6A3
SCHEMBL2146997 0.68 PGR (0.53) PGRS100A4SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7446216-B2 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-11-04 US disclosed
US-20060183874-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060183874-A1 Halogen substituted metallocene compounds for olefin polymerization B2M, CDYL, MLX PGR 1659/4885S100A4 921/4885SLC6A2 4466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.