SCHEMBL500370

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5365120	0.91	TAAR1 (0.44)	TAAR1IDO1TSHRHTTALDH1A1
	SCHEMBL31245544	0.86	TAAR1 (0.54)	TAAR1IDO1TSHRHTTALDH1A1
	SCHEMBL2541735	0.86	TAAR1 (0.54)	TAAR1IDO1TSHRHTTALDH1A1
	SCHEMBL9331124	0.86	TAAR1 (0.58)	TAAR1IDO1TSHRALDH1A1PYCR1
	SCHEMBL500785	0.82	IDO1 (0.53)	TAAR1IDO1TSHRHTTALDH1A1
	SCHEMBL27320452	0.81	TAAR1 (0.42)	TAAR1IDO1TSHRHTTALDH1A1
	SCHEMBL2400375	0.80	IDO1 (0.55)	TAAR1IDO1TSHRHTTALDH1A1
	SCHEMBL534456	0.78	TAAR1 (0.50)	TAAR1IDO1TSHRHTTALDH1A1
	SCHEMBL7340197	0.78	TAAR1 (0.50)	TAAR1IDO1TSHRALDH1A1KMT2A
	SCHEMBL12837807	0.78	TAAR1 (0.50)	TAAR1IDO1TSHRHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.