Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.40 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.40 |
| ▸ | P2RY6 | Q15077 | 8/20 | 0.36 |
| ▸ | TK1 | P04183 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TK2 | O00142 | 2/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27528956 | 1.00 | SLC28A1 (0.40) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL629554 | 1.00 | SLC28A1 (0.40) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL6035978 | 0.91 | SLC28A1 (0.43) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL1009600 | 0.89 | SLC28A1 (0.40) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL29777381 | 0.89 | SLC28A1 (0.40) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL8098949 | 0.87 | SLC28A1 (0.43) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL8170876 | 0.87 | SLC28A1 (0.43) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL15414027 | 0.87 | SLC28A1 (0.39) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL7394363 | 0.85 | P2RY6 (0.46) | P2RY6 | |
| SCHEMBL11202241 | 0.82 | POLB (0.41) | P2RY6NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419968-B1 | Methods for treating therapy-resistant tumors | CELMED ONCOLOGY (USA), INC. (CA) | 2008-09-02 | — | — | US | disclosed |
| EP-1363928-A1 | PROCESS FOR THE PREPARATION OF (E)-5-(2-BROMOVINYL)-2'-DEOXYURIDINE | Menarini Ricerche S.p.A. (IT) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002068443-A1 | PROCESS FOR THE PREPARATION OF (E)-5-(2-BROMOVINYL)-2'-DEOXYURIDINE | MENARINI RICERCHE S.P.A. (IT) | 2002-09-06 | — | — | WO | disclosed |
| EP-0104857-A1 | Deoxyuridine compounds, methods for preparing them and their use in medicine | BEECHAM GROUP PLC (GB) | 1984-04-04 | — | — | EP | disclosed |