SCHEMBL629554

SCHEMBL629554

O=c1ccn([C@@]2(C=CBr)C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.40
SLC28A2 O43868 1/20 0.40
SLC29A1 Q99808 1/20 0.40
SLC28A3 Q9HAS3 1/20 0.40
P2RY6 Q15077 8/20 0.36
TK1 P04183 3/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TK2 O00142 2/20 0.32
P2RY14 Q15391 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27528956 1.00 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL5004102 1.00 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL6035978 0.91 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL1009600 0.89 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL29777381 0.89 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL8098949 0.87 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL8170876 0.87 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL15414027 0.87 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL7394363 0.85 P2RY6 (0.46) P2RY6
SCHEMBL11202241 0.82 POLB (0.41) P2RY6NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 666 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367301-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TRIPLE-NEGATIVE BREAST CANCER, COMPRISING OLIGONUCLEOTIDE AS ACTIVE INGREDIENT INTEROLIGO CORPORATION (KR) 2025-12-04 US claimed
US-12448624-B2 Modified nucleic acid having improved treatment efficacy, and anticancer pharmaceutical composition containing same INTEROLIGO CORPORATION (KR) 2025-10-21 US claimed
CN-112888700-B Modified nucleic acid having improved therapeutic efficacy and anticancer pharmaceutical composition containing the same 因特欧力多公司 2025-03-04 CN claimed
US-20250049927-A1 MODIFIED OLIGONUCLEOTIDE-DRUG CONJUGATE AND USE THEREOF INTEROLIGO CORPORATION. (KR) 2025-02-13 US claimed
EP-4450092-A1 MODIFIED OLIGONUCLEOTIDE-DRUG CONJUGATE AND USE THEREOF Interoligo Corporation (KR) 2024-10-23 EP claimed
US-20240270780-A1 PROTEOLYSIS TARGETING COMPOUND WITH TISSUE TARGETING CAPABILITY AND USE THEREOF TAI BI DI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) 2024-08-15 US claimed
CN-118382461-A Modified oligonucleotide-drug conjugates and uses thereof 因特欧力多公司 2024-07-23 CN claimed
EP-4382134-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TRIPLE-NEGATIVE BREAST CANCER, COMPRISING OLIGONUCLEOTIDE AS ACTIVE INGREDIENT Interoligo Corporation. (KR) 2024-06-12 EP claimed
CN-117835987-A Pharmaceutical composition for preventing or treating triple negative breast cancer containing oligonucleotide as active ingredient 因特欧力多公司 2024-04-05 CN claimed
WO-2023113243-A1 MODIFIED OLIGONUCLEOTIDE-DRUG CONJUGATE AND USE THEREOF 인터올리고 주식회사 2023-06-22 WO claimed
CN-1082894-A The anti-viral pharmaceutical compositions of vagina administration L C PHARCHEM LTD (CY) 1994-03-02 CN claimed
WO-1993023094-A1 USE OF HYDROGELS TO FIX BONE REPLACEMENTS M.U.R.S.T., ITALIAN MINISTRY FOR UNIVERSITIES AND SCIENTIFIC AND TECHNOLOGICAL RESEARCH (IT) 1993-11-25 WO claimed
WO-1993018763-A1 COMPOSITIONS OF N-(PHOSPHONOACETYL)-L-ASPARTIC ACID AND METHODS OF THEIR USE AS BROAD SPECTRUM ANTIVIRALS U.S. BIOSCIENCE, INC. (US) 1993-09-30 WO claimed
WO-1993002662-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITIONS FOR VAGINAL ADMINISTRATION L.C. PHARCHEM LTD. (CY) 1993-02-18 WO claimed
EP-0226029-B1 THYMIDINE KINASE DELETION MUTANTS OF BOVINE HERPESVIRUS-1, VACCINES AGAINST INFECTIOUS BOVINE RHINOTRACHEITIS CONTAINING SAME AND METHODS FOR THE PRODUCTION AND USE OF THE SAME NOVAGENE, INC. (US) 1992-03-11 EP claimed
US-4902678-A SYNERGISTIC MIXTURE; HERPES VIRUS INFECTIONS SYNTEX (U.S.A.) INC. (US) 1990-02-20 US claimed
EP-0101441-B1 ANTI-VIRAL COMPOSITIONS SYNTEX (U.S.A.) INC. (US) 1987-01-14 EP claimed
EP-0101441-A4 ANTI-VIRAL COMPOSITIONS. ENS BIO LOGICALS INC (CA) 1985-04-11 EP claimed
EP-0101441-A1 ANTI-VIRAL COMPOSITIONS. ENS BIO LOGICALS INC (CA) 1984-02-29 EP claimed
WO-1983002723-A1 ANTI-VIRAL COMPOSITIONS SMITH, KENDALL, O. 1983-08-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240270780-A1 PROTEOLYSIS TARGETING COMPOUND WITH TISSUE TARGETING CAPABILITY AND USE THEREOF ASGR1, ADRM1, PSMB11 SLC28A1 3255/4885SLC28A2 3237/4885SLC29A1 3269/4885
US-20250367301-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TRIPLE-NEGATIVE BREAST CANCER, COMPRISING OLIGONUCLEOTIDE AS ACTIVE INGREDIENT BRCA1, POLN, POLRMT SLC28A1 853/4885SLC28A2 1003/4885SLC29A1 964/4885
US-20250049927-A1 MODIFIED OLIGONUCLEOTIDE-DRUG CONJUGATE AND USE THEREOF DCLRE1B, DUT, DCTD SLC28A1 224/4885SLC28A2 247/4885SLC29A1 39/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.