SCHEMBL8170876

SCHEMBL8170876

O=C[C@]1(n2ccc(=O)[nH]c2=O)C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.43
SLC28A2 O43868 1/20 0.43
SLC29A1 Q99808 1/20 0.43
SLC28A3 Q9HAS3 1/20 0.43
P2RY6 Q15077 9/20 0.38
P2RY14 Q15391 1/20 0.33
DUT P33316 3/20 0.32
P2RY2 P41231 2/20 0.32
P2RY4 P51582 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8098949 0.91 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL27528956 0.87 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL6035978 0.87 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL629554 0.87 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL29777381 0.87 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL1009600 0.87 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL5004102 0.87 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL15414027 0.85 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL51723 0.81 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL28786348 0.81 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1041159-A2 Method, oligonucleotides suitable for the degradation of in vitro synthesized nucleic acid molecules MIRA Diagnostika GmbH (DE) 2000-10-04 EP disclosed