SCHEMBL6035978

SCHEMBL6035978

O=c1ccn([C@@]2(C=CI)C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.43
SLC28A2 O43868 1/20 0.43
SLC29A1 Q99808 1/20 0.43
SLC28A3 Q9HAS3 1/20 0.43
P2RY6 Q15077 9/20 0.36
P2RY14 Q15391 4/20 0.33
P2RY2 P41231 3/20 0.32
P2RY4 P51582 1/20 0.31
TK1 P04183 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL629554 0.91 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL27528956 0.91 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL5004102 0.91 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL15414027 0.89 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL29777381 0.89 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL1009600 0.89 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL8098949 0.87 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL8170876 0.87 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL8763033 0.82 SLC28A1 (0.34) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL8763022 0.82 SLC28A1 (0.34) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0101441-B1 ANTI-VIRAL COMPOSITIONS SYNTEX (U.S.A.) INC. (US) 1987-01-14 EP claimed
EP-0101441-A4 ANTI-VIRAL COMPOSITIONS. ENS BIO LOGICALS INC (CA) 1985-04-11 EP claimed
EP-0101441-A1 ANTI-VIRAL COMPOSITIONS. ENS BIO LOGICALS INC (CA) 1984-02-29 EP claimed
WO-1983002723-A1 ANTI-VIRAL COMPOSITIONS SMITH, KENDALL, O. 1983-08-18 WO claimed
US-20060223775-A1 Nucleotide sequence for treating cancer and infection ZEICHER MARC 2006-10-05 US disclosed
EP-0673430-A1 NUCLEOTIDE SEQUENCE FOR TREATING CANCER AND INFECTION Z. COMPANY S.A. (BE) 1995-09-27 EP disclosed
WO-1994013823-A1 NUCLEOTIDE SEQUENCE FOR TREATING CANCER AND INFECTION Z. COMPANY S.A. (BE) 1994-06-23 WO disclosed