SCHEMBL1009600

SCHEMBL1009600

O=c1ccn([C@@]2(C=CCl)C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.40
SLC28A2 O43868 1/20 0.40
SLC29A1 Q99808 1/20 0.40
SLC28A3 Q9HAS3 1/20 0.40
P2RY6 Q15077 9/20 0.36
P2RY14 Q15391 1/20 0.32
DUT P33316 2/20 0.31
POLA1 P09884 1/20 0.31
P2RY2 P41231 1/20 0.30
P2RY4 P51582 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27528956 0.89 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL6035978 0.89 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL5004102 0.89 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL629554 0.89 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL29777381 0.89 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL8098949 0.87 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL8170876 0.87 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL15414027 0.87 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL414705 0.80 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL8763033 0.80 SLC28A1 (0.34) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119033822-A Compositions and methods for inhibiting seizures 加利福尼亚大学董事会 2024-11-29 CN disclosed
CN-110325196-B Compositions and methods for inhibiting seizures 加利福尼亚大学董事会 2024-08-27 CN disclosed
CN-101198320-B Herpesvirus-derived therapeutic agent for pain JUNTENDO EDUCATIONAL FOUNDATION 2012-03-07 CN disclosed
US-7897645-B2 Herpesvirus-derived therapeutic agent for pain TAIHO PHARMACEUTICAL CO., LTD. (JP) 2011-03-01 US disclosed
EP-1908467-B1 AGENT FOR TREATING HERPESVIRUS-DERIVED PAIN JUNTENDO EDUCATIONAL FOUNDATION (JP) 2011-01-05 EP disclosed
US-20090149532-A1 HERPESVIRUS-DERIVED THERAPEUTIC AGENT FOR PAIN TAIHO PHARMACEUTICAL CO., LTD. (JP) 2009-06-11 US disclosed
CN-101198320-A Herpesvirus-derived therapeutic agent for pain JUNTENDO EDUCATIONAL FOUNDATIO (JP) 2008-06-11 CN disclosed
EP-1908467-A1 HERPESVIRUS-DERIVED THERAPEUTIC AGENT FOR PAIN Juntendo Educational Foundation (JP) 2008-04-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149532-A1 HERPESVIRUS-DERIVED THERAPEUTIC AGENT FOR PAIN RPL35, DDOST, HSPB1 SLC28A1 4650/4885SLC28A2 4767/4885SLC29A1 4578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.