SCHEMBL5004820

SCHEMBL5004820

COC(=O)C12C[C]3CC(CC(C(=O)O)(C3)C1)C2

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 2/20 0.32
GLA P06280 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
MEN1 O00255 1/20 0.30
RBP4 P02753 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2939176 0.94 GLA (0.35) ALDH1A1KMT2AGLANPSR1MEN1
SCHEMBL2536217 0.87 PKM (0.35) ALDH1A1KMT2AMEN1RBP4
SCHEMBL2537545 0.83 ABL1 (0.36) ALDH1A1GLANPSR1
SCHEMBL4034729 0.83 MEN1 (0.35) KMT2AGLAMEN1
SCHEMBL5084537 0.78 ALDH1A1 (0.39) ALDH1A1KMT2AGLANPSR1MEN1
SCHEMBL5082232 0.78 ALDH1A1 (0.39) ALDH1A1KMT2AGLANPSR1MEN1
SCHEMBL6229112 0.78 MEN1 (0.37) ALDH1A1KMT2AMEN1
SCHEMBL1772638 0.77 GLA (0.42) ALDH1A1KMT2AGLANPSR1MEN1
SCHEMBL2536300 0.76 HSD11B1 (0.34)
SCHEMBL163910 0.75 ALDH1A1 (0.51) ALDH1A1KMT2AGLANPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7452655-B2 Acrylic copolymer and radiation-sensitive resin composition JSR CORPORATION (JP) 2008-11-18 US disclosed
US-20060074139-A1 Acrylic copolymer and radiation-sensitive resin composition JSR CORPORATION (JP) 2006-04-06 US disclosed