SCHEMBL2536217

SCHEMBL2536217

O=C(O)C12C[C]3CC(C1)CC(C(=O)O)(C3)C2

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GAA P10253 1/20 0.35
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 1/20 0.32
RBP4 P02753 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2536300 0.87 HSD11B1 (0.34) PKML3MBTL1GAA
SCHEMBL5004820 0.87 ALDH1A1 (0.33) ALDH1A1RBP4MEN1KMT2A
SCHEMBL6229112 0.86 MEN1 (0.37) PKML3MBTL1GAAALDH1A1SMN1; SMN2
SCHEMBL1772267 0.79 L3MBTL1 (0.39) PKML3MBTL1GAAALDH1A1SMN1; SMN2
SCHEMBL2939176 0.77 GLA (0.35) GAAALDH1A1LMNAMEN1KMT2A
SCHEMBL282760 0.74 PKM (0.42) PKML3MBTL1GAAALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL4580832 0.72 PKM (0.46) PKML3MBTL1GAAALDH1A1SMN1; SMN2
SCHEMBL164232 0.70 L3MBTL1 (0.58) PKML3MBTL1GAAALDH1A1SMN1; SMN2
SCHEMBL13589980 0.70 L3MBTL1 (0.58) PKML3MBTL1GAAALDH1A1SMN1; SMN2
SCHEMBL14493665 0.70 L3MBTL1 (0.58) PKML3MBTL1GAAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8440384-B2 Compound, salt, and radiation-sensitive resin composition JSR CORPORATION (JP) 2013-05-14 US disclosed
US-20130045446-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING A RESIST PATTERN AND SULFONIUM COMPOUND JSR CORPORATION (JP) 2013-02-21 US disclosed
US-8043786-B2 Acid generators, sulfonic acids, sulfonyl halides, and radiation sensitive resin compositions JSR CORPORATION (JP) 2011-10-25 US disclosed
EP-1586594-B1 ACRYLIC COPOLYMER AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORP (JP) 2010-09-15 EP disclosed
US-20100221659-A1 COMPOUND, SALT, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-09-02 US disclosed
US-7452655-B2 Acrylic copolymer and radiation-sensitive resin composition JSR CORPORATION (JP) 2008-11-18 US disclosed
US-7217492-B2 Onium salt compound and radiation-sensitive resin composition JSR CORPORATION (JP) 2007-05-15 US disclosed
US-20070054214-A1 Acid generators, sulfonic acids, sulfonyl halides, and radiation sensitive resin compositions JSR CORPORATION (JP) 2007-03-08 US disclosed
US-20060074139-A1 Acrylic copolymer and radiation-sensitive resin composition JSR CORPORATION (JP) 2006-04-06 US disclosed
EP-1600437-A1 ACID GENERATORS, SULFONIC ACIDS, SULFONYL HALIDES, AND RADIATION-SENSITIVE RESIN COMPOSITIONS JSR Corporation (JP) 2005-11-30 EP disclosed
US-20050053861-A1 Onium salt compound and radiation-sensitive resin composition JSR CORPORATION (JP) 2005-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100221659-A1 COMPOUND, SALT, AND RADIATION-SENSITIVE RESIN COMPOSITION AFF1, RER1, AFF4 PKM 4428/4885L3MBTL1 2200/4885GAA 4786/4885
US-20130045446-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING A RESIST PATTERN AND SULFONIUM COMPOUND RAD51, RER1, SEM1 PKM 4309/4885L3MBTL1 2474/4885GAA 2109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.