Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5009225 | 0.83 | MMP2 (0.36) | ALDH1A1HPGDMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL5005961 | 0.79 | MMP8 (0.44) | ALDH1A1LMNAHPGDMAPTGSK3B | |
| SCHEMBL14691121 | 0.76 | MAPT (0.38) | ALDH1A1MAPTSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL16116754 | 0.69 | CYP1A2 (0.38) | ALDH1A1 | |
| SCHEMBL22341263 | 0.68 | CYP1A2 (0.37) | — | |
| SCHEMBL3541280 | 0.68 | CYP1A2 (0.37) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5011069 | 0.68 | GSK3B (0.36) | ALDH1A1LMNAHPGDMAPTTAAR1 | |
| SCHEMBL29603054 | 0.66 | CYP1A2 (0.34) | MAPT | |
| SCHEMBL1748043 | 0.65 | ALDH1A1 (0.38) | ALDH1A1LMNAHPGDMAPTTAAR1 | |
| SCHEMBL1748045 | 0.65 | ALDH1A1 (0.38) | ALDH1A1LMNAHPGDMAPTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423156-B2 | Preparation and use of aryl alkyl acid derivatives for the treatment of obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2008-09-09 | — | — | US | disclosed |