Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011043 | 0.84 | MMP2 (0.34) | AKR1B1MAPTHPGDL3MBTL1 | |
| SCHEMBL5009236 | 0.74 | CYP2C19 (0.31) | AKR1B1 | |
| SCHEMBL1747924 | 0.70 | ALDH1A1 (0.43) | GSK3BALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL5009223 | 0.69 | — | — | |
| SCHEMBL5006816 | 0.68 | ALDH1A1 (0.41) | GSK3BALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL1748001 | 0.65 | OPRM1 (0.44) | GSK3BALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL12265857 | 0.62 | KMT2A (0.44) | GSK3BALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL3392114 | 0.62 | KMT2A (0.51) | GSK3BALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL2635792 | 0.61 | HAO1 (0.63) | GSK3BALDH1A1KMT2AMAPTHDAC1 | |
| SCHEMBL22921696 | 0.60 | AKR1B1 (0.40) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423156-B2 | Preparation and use of aryl alkyl acid derivatives for the treatment of obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2008-09-09 | — | — | US | disclosed |