Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.68 |
| ▸ | MMP2 | P08253 | 1/20 | 0.64 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | DPYD | Q12882 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thymine SCHEMBL574783 | 0.84 | ATAD2 (0.70) | ATAD2MMP2CRBNDPYDALDH1A1 | |
| Thymine SCHEMBL5235 | 0.82 | — | — | |
| Thymine SCHEMBL17201833 | 0.82 | ATAD2 (1.00) | ATAD2DPYDALDH1A1GAALMNA | |
| Thymine SCHEMBL750450 | 0.82 | ATAD2 (1.00) | ATAD2DPYDALDH1A1GAALMNA | |
| Thymine SCHEMBL15323914 | 0.82 | ATAD2 (1.00) | ATAD2DPYDALDH1A1GAALMNA | |
| Thymine SCHEMBL29669526 | 0.82 | — | — | |
| Thymine SCHEMBL23388801 | 0.80 | ATAD2 (0.95) | ATAD2DPYDALDH1A1GAALMNA | |
| Thymine SCHEMBL8649294 | 0.80 | ATAD2 (0.95) | ATAD2DPYDALDH1A1GAALMNA | |
| Thymine SCHEMBL4811815 | 0.80 | — | — | |
| Thymine SCHEMBL935833 | 0.80 | ATAD2 (0.95) | ATAD2DPYDALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140303008-A1 | COLORECTAL CANCER ASSOCIATED CIRCULATING NUCLEIC ACID BIOMARKERS | CHRONIX BIOMEDICAL | 2014-10-09 | — | — | US | disclosed |
| US-7459531-B2 | 50 Human secreted proteins | HUMAN GENOME SCIENCES, INC. (US) | 2008-12-02 | — | — | US | disclosed |
| US-20070154910-A1 | Glycosylated polypeptide of given amino acid sequence; treatment of genetic diseases such as muscular dystrophy and cystic fibrosis | HUMAN GENOME SCIENCES, INC. (US) | 2007-07-05 | — | — | US | disclosed |
| US-20060248605-A1 | Beta-amyloid peptide-binding proteins and polynucleotides encoding the same | WYETH (US) | 2006-11-02 | — | — | US | disclosed |