Thymine

Thymine

SCHEMBL574783

Cc1c[nH]c(=O)[nH]c1=O.O=c1cc[nH]c(=O)[nH]1

nearest known ligand 0.70

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATAD2 Q6PL18 1/20 0.70
CRBN Q96SW2 1/20 0.63
MMP2 P08253 1/20 0.41
DPYD Q12882 5/20 0.39
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.39
TP53 P04637 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
CYP19A1 P11511 1/20 0.39
TSHR P16473 1/20 0.39
THPO P40225 1/20 0.39
MTOR P42345 1/20 0.39
HTT P42858 1/20 0.39
HBB P68871 1/20 0.39
PMP22 Q01453 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TYMP P19971 1/20 0.36
GSK3B P49841 1/20 0.36
BACE1 P56817 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thymine SCHEMBL17144680 0.88 ATAD2 (0.54) ATAD2CRBNMMP2DPYDALDH1A1
Thymine SCHEMBL3657360 0.84 ATAD2 (0.50) ATAD2CRBNMMP2LMNAHTT
Thymine SCHEMBL750450 0.84 ATAD2 (1.00) ATAD2DPYDALDH1A1GAALMNA
Thymine SCHEMBL5235 0.84
Thymine SCHEMBL29669526 0.84
Thymine SCHEMBL17201833 0.84 ATAD2 (1.00) ATAD2DPYDALDH1A1GAALMNA
Thymine SCHEMBL15323914 0.84 ATAD2 (1.00) ATAD2DPYDALDH1A1GAALMNA
Thymine SCHEMBL5007601 0.84 ATAD2 (0.68) ATAD2CRBNMMP2DPYDALDH1A1
Thymine SCHEMBL23388801 0.82 ATAD2 (0.95) ATAD2DPYDALDH1A1GAALMNA
Thymine SCHEMBL2724033 0.82 ATAD2 (0.95) ATAD2DPYDALDH1A1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 608 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4728092-A1 DETERMINATION OF MODIFIED CYTOSINES Illumina, Inc. (US) 2026-04-22 EP claimed
EP-4494151-A1 METHODS OF DETERMINING SEQUENCE INFORMATION Illumina, Inc. (US) 2025-01-22 EP claimed
WO-2024256581-A1 DETERMINATION OF MODIFIED CYTOSINES ILLUMINA, INC. (US) 2024-12-19 WO claimed
US-20240352515-A1 METHODS OF BASE CALLING NUCLEOBASES ILLUMINA INC (US) 2024-10-24 US claimed
US-20240301464-A1 CONCURRENT SEQUENCING OF FORWARD AND REVERSE COMPLEMENT STRANDS ON SEPARATE POLYNUCLEOTIDES FOR METHYLATION DETECTION ILLUMINA INC (US) 2024-09-12 US claimed
US-20240287578-A1 CONCURRENT SEQUENCING OF FORWARD AND REVERSE COMPLEMENT STRANDS ON CONCATENATED POLYNUCLEOTIDES FOR METHYLATION DETECTION ILLUMINA, INC. 2024-08-29 US claimed
CN-118086471-A Methods, compositions, systems, instruments and kits for nucleic acid amplification 生命技术公司 2024-05-28 CN claimed
EP-4341426-A2 CONCURRENT SEQUENCING OF FORWARD AND REVERSE COMPLEMENT STRANDS ON SEPARATE POLYNUCLEOTIDES FOR METHYLATION DETECTION Illumina, Inc. (US) 2024-03-27 EP claimed
EP-4341435-A1 METHODS OF BASE CALLING NUCLEOBASES Illumina, Inc. (US) 2024-03-27 EP claimed
EP-4341425-A2 CONCURRENT SEQUENCING OF FORWARD AND REVERSE COMPLEMENT STRANDS ON CONCATENATED POLYNUCLEOTIDES FOR METHYLATION DETECTION Illumina, Inc. (US) 2024-03-27 EP claimed
WO-2023175037-A2 CONCURRENT SEQUENCING OF FORWARD AND REVERSE COMPLEMENT STRANDS ON SEPARATE POLYNUCLEOTIDES FOR METHYLATION DETECTION ILLUMINA, INC. (US) 2023-09-21 WO claimed
EP-1399108-A2 PREPARATION OF A THERAPEUTIC COMPOSITION Advanced Viral Research Corp. (US) 2004-03-24 EP claimed
US-20030158107-A1 Preparation of a therapeutic composition ADVANCED VIRAL RESEARCH CORP. 2003-08-21 US claimed
US-20030134782-A1 Preparation of a therapeutic composition ADVANCED VIRAL RESEARCH CORP. 2003-07-17 US claimed
EP-0679657-B1 Nucleosides and oligonucleotides containing 2'-ether groups NOVARTIS AG (CH) 2003-07-09 EP claimed
US-6528098-B2 Viricides ADVANCED VIRAL RESEARCH CORP. 2003-03-04 US claimed
WO-2002056833-A2 PREPARATION OF A THERAPEUTIC COMPOSITION ADVANCED VIRAL RESEARCH CORP. (US) 2002-07-25 WO claimed
US-20020004579-A1 Preparation of a therapeutic composition ADVANCED VIRAL RESEARCH CORP. 2002-01-10 US claimed
EP-0040099-A1 Polynucleotide synthesis ens BIO LOGICALS INC. (CA) 1981-11-18 EP claimed
US-4205134-A Carrier for liquid chromatography TOYO SODA MANUFACTURING COMPANY, LTD. (JP) 1980-05-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030158107-A1 Preparation of a therapeutic composition VIP, FCGR3B, FCGRT ATAD2 4464/4885CRBN 4104/4885MMP2 3527/4885
US-20020004579-A1 Preparation of a therapeutic composition VIP, FCGR3B, FCGRT ATAD2 4464/4885CRBN 4104/4885MMP2 3527/4885
US-20030134782-A1 Preparation of a therapeutic composition VIP, FCGR3B, FCGRT ATAD2 4464/4885CRBN 4104/4885MMP2 3527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.