Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 1.00 |
| ▸ | RAB9A | P51151 | 9/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2241896 | 0.84 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL2246129 | 0.82 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL30354865 | 0.82 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL13744788 | 0.82 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL2245506 | 0.82 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL2248644 | 0.82 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL15063375 | 0.81 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL7686538 | 0.81 | RAB9A (0.72) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL7688380 | 0.81 | RAB9A (0.76) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL20103550 | 0.79 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470827-B2 | Composition for the vapor phase dehydrohalogenation of 1,1,2-trihaloethane to 1,1-dihaloethylene and methods for preparing and using such composition | PPG INDUSTRIES OHIO, INC. (US) | 2008-12-30 | — | — | US | claimed |
| US-20080242902-A1 | Composition For the Vapor Phase Dehydrohalogenation of 1,1,2-Trihaloethane To 1,1-Dihaloethylene and Methods For Preparing and Using Such Composition | PPG INDUSTRIES OHIO, INC (US) | 2008-10-02 | — | — | US | claimed |
| WO-2006132625-A1 | COMPOSITION FOR THE VAPOR PHASE DEHYDROHALOGENATION OF 1,1,2-TRIHALOETHANE TO 1,1-DIHALOETHYLENE AND METHODS FOR PREPARING AND USING SUCH COMPOSITIONS | PPG INDUSTRIES OHIO, INC. (US) | 2006-12-14 | — | — | WO | claimed |
| US-7470827-B2 | Composition for the vapor phase dehydrohalogenation of 1,1,2-trihaloethane to 1,1-dihaloethylene and methods for preparing and using such composition | PPG INDUSTRIES OHIO, INC. (US) | 2008-12-30 | — | — | US | disclosed |
| US-20080242902-A1 | Composition For the Vapor Phase Dehydrohalogenation of 1,1,2-Trihaloethane To 1,1-Dihaloethylene and Methods For Preparing and Using Such Composition | PPG INDUSTRIES OHIO, INC (US) | 2008-10-02 | — | — | US | disclosed |
| WO-2006132625-A1 | COMPOSITION FOR THE VAPOR PHASE DEHYDROHALOGENATION OF 1,1,2-TRIHALOETHANE TO 1,1-DIHALOETHYLENE AND METHODS FOR PREPARING AND USING SUCH COMPOSITIONS | PPG INDUSTRIES OHIO, INC. (US) | 2006-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242902-A1 | Composition For the Vapor Phase Dehydrohalogenation of 1,1,2-Trihaloethane To 1,1-Dihaloethylene and Methods For Preparing and Using Such Composition | CYP2E1, CYP1A1, HDHD5 | NPC1 2698/4885RAB9A 3877/4885SMN1; SMN2 4434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.