Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 6/20 | 0.50 |
| ▸ | DRD4 | P21917 | 11/20 | 0.48 |
| ▸ | DRD2 | P14416 | 11/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4252469 | 0.90 | CACNA1G (0.51) | CACNA1GDRD2 | |
| SCHEMBL4245823 | 0.90 | CACNA1G (0.54) | CACNA1GDRD4DRD2 | |
| SCHEMBL4252512 | 0.89 | CACNA1G (0.51) | CACNA1GDRD4DRD2 | |
| SCHEMBL5011504 | 0.87 | DRD4 (0.47) | CACNA1GDRD4DRD2KDM4EGAA | |
| SCHEMBL4245561 | 0.86 | SIRT6 (0.41) | CACNA1GDRD2 | |
| SCHEMBL3219434 | 0.86 | KDM4E (0.53) | DRD4DRD2KDM4EGAA | |
| SCHEMBL5009521 | 0.84 | CACNA1G (0.57) | CACNA1GDRD4DRD2KDM4EGAA | |
| SCHEMBL3232218 | 0.84 | KDM4E (0.53) | DRD4DRD2KDM4EGAA | |
| SCHEMBL4245578 | 0.83 | CACNA1G (0.49) | CACNA1GDRD4DRD2GAA | |
| SCHEMBL13996867 | 0.83 | CACNA1G (0.49) | CACNA1GDRD4DRD2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312253-A1 | Pharmaceutical compositions containing pyrazole derivatives for treating as serotonin antagonist | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-12-18 | — | — | US | claimed |
| US-20080312253-A1 | Pharmaceutical compositions containing pyrazole derivatives for treating as serotonin antagonist | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-12-18 | — | — | US | disclosed |
| US-20080312253-A1 | Pharmaceutical compositions containing pyrazole derivatives for treating as serotonin antagonist | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312253-A1 | Pharmaceutical compositions containing pyrazole derivatives for treating as serotonin antagonist | HTR3A, HTR3B, HTR3E | CACNA1G 1316/4885DRD4 225/4885DRD2 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.