Phosphoric Acid

Phosphoric Acid

SCHEMBL5010353

CCCCCCCC(=O)NCCCN(C)Cc1ccccc1.CCCCCCCC(=O)NCCCN(C)Cc1ccccc1.CCCCCCCC(=O)NCCCN(C)Cc1ccccc1.O=P(O)(O)O

nearest known ligand 0.60

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 10/20 0.60
TMEM97 Q5BJF2 9/20 0.60
ACKR3 P25106 3/20 0.59
APP P05067 1/20 0.56
EPHX2 P34913 1/20 0.55
DNM1 Q05193 1/20 0.54
HPGD P15428 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9320586 0.95 ACKR3 (0.64) SIGMAR1TMEM97ACKR3APPEPHX2
Hydrochloric Acid SCHEMBL9872490 0.94 ACKR3 (0.63) SIGMAR1TMEM97ACKR3APPEPHX2
Hydrochloric Acid SCHEMBL27718505 0.94 ACKR3 (0.63) SIGMAR1TMEM97ACKR3APPEPHX2
SCHEMBL15362879 0.89 EPHX2 (0.67) SIGMAR1TMEM97ACKR3EPHX2HPGD
SCHEMBL15362883 0.82 EPHX2 (0.67) SIGMAR1TMEM97ACKR3APPEPHX2
SCHEMBL10108806 0.81 ACKR3 (0.59) SIGMAR1TMEM97ACKR3APP
SCHEMBL9549092 0.80 EPHX2 (0.63) EPHX2DNM1HPGD
Hydrochloric Acid SCHEMBL11666142 0.80 GAA (0.57) ACKR3APPEPHX2DNM1HPGD
Phosphoric Acid SCHEMBL340431 0.78 DNM1 (0.88) EPHX2DNM1
Phosphoric Acid SCHEMBL9843964 0.78 DNM1 (0.88) EPHX2DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1948724-A1 LIGHT CURE OF CATIONIC INK ON ACIDIC SUBSTRATES Gerber Scientific International, Inc. (US) 2008-07-30 EP disclosed
WO-2007058651-A1 LIGHT CURE OF CATIONIC INK ON ACIDIC SUBSTRATES GERBER SCIENTIFIC INTERNATIONAL, INC. (US) 2007-05-24 WO disclosed