Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16831416 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTPTPN1GABRR1GABRR2 | |
| SCHEMBL2552670 | 0.92 | ALDH1A1 (0.50) | ALDH1A1PTPN1HCAR2TBXAS1LPAR3 | |
| SCHEMBL2549349 | 0.92 | ALDH1A1 (0.50) | ALDH1A1PTPN1HCAR2TBXAS1LPAR3 | |
| SCHEMBL700035 | 0.92 | ALDH1A1 (0.50) | ALDH1A1PTPN1HCAR2TBXAS1LPAR3 | |
| SCHEMBL700036 | 0.92 | ALDH1A1 (0.50) | ALDH1A1PTPN1HCAR2TBXAS1LPAR3 | |
| SCHEMBL2552304 | 0.92 | ALDH1A1 (0.50) | ALDH1A1PTPN1HCAR2TBXAS1LPAR3 | |
| SCHEMBL4888380 | 0.86 | — | — | |
| SCHEMBL9748238 | 0.86 | — | — | |
| SCHEMBL5010352 | 0.83 | MAPT (0.40) | ALDH1A1MAPTTSHRLPAR3 | |
| SCHEMBL10580328 | 0.83 | MAPT (0.40) | ALDH1A1MAPTPTPN1TSHRLPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999295-A | Polymer for water repellent, water repellent composition, and water repellent treated product | 日油株式会社 | 2024-05-07 | — | — | CN | disclosed |
| US-20190002454-A1 | NRF2 Regulators | GLAXOSMITHKLINE IP DEV LTD (GB) | 2019-01-03 | — | — | US | disclosed |
| US-10144731-B2 | Nrf2 regulators | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-12-04 | — | — | US | disclosed |
| US-20160318917-A1 | NRF2 REGULATORS | ASTEX THERAPEUTICS LIMITED (GB) | 2016-11-03 | — | — | US | disclosed |
| EP-3083614-A1 | NRF2 REGULATORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015092713-A1 | NRF2 REGULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2015-06-25 | — | — | WO | disclosed |
| US-8450033-B2 | Electrography; facsimiles, printers, copiers; polyurethanes | RICOH COMPANY, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| US-20080138728-A1 | LATENT ELECTROSTATIC IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE USING THE SAME | RICOH COMPANY, LTD. (JP) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002454-A1 | NRF2 Regulators | NFE2L2, KEAP1, NQO1 | ALDH1A1 799/4885MAPT 1861/4885PTPN1 3313/4885 |
| US-20160318917-A1 | NRF2 REGULATORS | NFE2L2, KEAP1, NQO1 | ALDH1A1 799/4885MAPT 1861/4885PTPN1 3313/4885 |
| US-10144731-B2 | Nrf2 regulators | NFE2L2, KEAP1, NQO1 | ALDH1A1 799/4885MAPT 1861/4885PTPN1 3313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.