Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 15/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.66 |
| ▸ | PTGES | O14684 | 2/20 | 0.65 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010683 | 0.89 | HTR2A (0.70) | TAS2R14MEN1KMT2AMAPTCXCR3 | |
| SCHEMBL1278616 | 0.87 | TAS2R14 (1.00) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL1278788 | 0.86 | TAS2R14 (0.97) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL6976163 | 0.84 | TAS2R14 (0.77) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL6300786 | 0.84 | TAS2R14 (0.77) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL24724004 | 0.82 | TAS2R14 (0.80) | TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL1279497 | 0.82 | TAS2R14 (1.00) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL1279183 | 0.82 | TAS2R14 (1.00) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL3814018 | 0.82 | TAS2R14 (0.73) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL984791 | 0.81 | TAS2R14 (0.71) | TAS2R14MEN1KMT2AMAPTCXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869968-B1 | Such as 3-(4-fluorophenyl)-4-(4-methysulphonylphenyl)-2-(3H)-oxazolone; for treating colorectal cancer, fevers, and inflammation | ALLMIRALL PRODESFARMA S.A. (ES) | 2005-03-22 | — | — | US | disclosed |