SCHEMBL5010716

SCHEMBL5010716

O=S(=O)(O)c1ccc(Cl)c(C2(C3(c4cc(S(=O)(=O)O)ccc4Cl)N=C(c4ccccc4)C(c4ccccc4)(c4ccccc4)N3)N=CC(c3ccccc3)=N2)c1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4256237 0.81
SCHEMBL4359690 0.77
SCHEMBL3967301 0.75
SCHEMBL490718 0.70 HDAC6 (0.40) HDAC6
SCHEMBL27680510 0.56 TSHR (0.47) HDAC6
SCHEMBL474108 0.53 APEX1 (0.48)
SCHEMBL29389290 0.53 APEX1 (0.48)
SCHEMBL341942 0.52 ALDH1A1 (0.42)
Fluoride SCHEMBL11757109 0.52 APEX1 (0.47)
Hydrochloric Acid SCHEMBL11167399 0.52 RAB9A (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1987396-A1 UV-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR WITH BENZOXAZOLE DERIVATIVE AND ANALOGUES THEREOF AS SENSITIZER Kodak Graphic Communications GmbH (DE) 2008-11-05 EP disclosed
WO-2007090550-A1 UV-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR WITH BENZOXAZOLE DERIVATIVE AND ANALOGUES THEREOF AS SENSITIZER KODAK GRAPHIC COMMUNICATIONS GMBH (DE) 2007-08-16 WO disclosed