Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2904772 | 0.84 | BCAT2 (0.52) | HNF4ABCAT2ALDH1A1HSD17B10HPGD | |
| SCHEMBL28380645 | 0.81 | HNF4A (0.56) | HNF4ABCAT2ALDH1A1HDAC4HDAC2 | |
| SCHEMBL28613771 | 0.81 | BCAT2 (0.50) | HNF4ABCAT2ALDH1A1HSD17B10HPGD | |
| SCHEMBL5010723 | 0.79 | HNF4A (0.53) | HNF4ABCAT2ALDH1A1HSD17B10HPGD | |
| Thiobenzoic Acid SCHEMBL7573638 | 0.78 | HNF4A (0.44) | HNF4ABCAT2ALDH1A1HSD17B10HPGD | |
| SCHEMBL225203 | 0.76 | HNF4A (0.71) | HNF4ABCAT2ALDH1A1HSD17B10HPGD | |
| SCHEMBL5010126 | 0.76 | HNF4A (0.50) | HNF4ABCAT2ALDH1A1HSD17B10HPGD | |
| SCHEMBL8778491 | 0.76 | HNF4A (0.60) | HNF4ABCAT2ALDH1A1HDAC4HDAC2 | |
| SCHEMBL5008857 | 0.74 | HNF4A (0.48) | HNF4ABCAT2ALDH1A1HSD17B10HPGD | |
| SCHEMBL5010686 | 0.74 | HNF4A (0.48) | HNF4ABCAT2ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458968-B2 | REACTING A CARBOXYLIC ACID COMPOUND WITH AN ALCOHOL OR MERCAPTAN, THEN PHOSPHORUS PENTASULFIDE | RENSSELAER POLYTECHNIC INSTITUTE | 2002-10-01 | — | — | US | claimed |
| US-20020019554-A1 | Dithiocarboxylic ester synthetic process | RENSSELAER POLYTECHNIC INSTITUTE | 2002-02-14 | — | — | US | claimed |
| US-6458968-B2 | REACTING A CARBOXYLIC ACID COMPOUND WITH AN ALCOHOL OR MERCAPTAN, THEN PHOSPHORUS PENTASULFIDE | RENSSELAER POLYTECHNIC INSTITUTE | 2002-10-01 | — | — | US | disclosed |
| US-20020019554-A1 | Dithiocarboxylic ester synthetic process | RENSSELAER POLYTECHNIC INSTITUTE | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019554-A1 | Dithiocarboxylic ester synthetic process | TST, PCCA, CTH | HNF4A 2588/4885BCAT2 1049/4885ALDH1A1 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.