2,6-Dichlorophenol

2,6-Dichlorophenol

SCHEMBL5010979

CC(C)(C)Br.Oc1c(Cl)cccc1Cl

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
CA2 P00918 2/20 0.44
ALDH1A1 P00352 6/20 0.42
HSP90AA1 P07900 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39
GABRA1 P14867 2/20 0.39
GABRB2 P47870 2/20 0.39
IDO1 P14902 1/20 0.38
LMNA P02545 2/20 0.38
RECQL P46063 2/20 0.38
HSD17B10 Q99714 2/20 0.38
TTR P02766 1/20 0.38
CYP3A4 P08684 1/20 0.38
MEN1 O00255 1/20 0.36
MAPK1 P28482 1/20 0.36
KMT2A Q03164 1/20 0.36
PDK1 Q15118 1/20 0.36
PDK2 Q15119 1/20 0.36
PDK3 Q15120 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,6-Dichlorophenol SCHEMBL8986495 0.86 TSHR (0.50) TSHRCA2ALDH1A1HSP90AA1CYP1A2
2,6-Dichlorophenol SCHEMBL65234 0.86
2,6-Dichlorophenol SCHEMBL30790427 0.83 TSHR (0.52) TSHRCA2ALDH1A1HSP90AA1CYP1A2
2,6-Dichlorophenol SCHEMBL10747747 0.83 TSHR (0.52) TSHRCA2ALDH1A1HSP90AA1CYP1A2
2,6-Dichlorophenol SCHEMBL30257485 0.83 TSHR (0.52) TSHRCA2ALDH1A1HSP90AA1CYP1A2
2,6-Dichlorophenol SCHEMBL949095 0.83 TSHR (0.52) TSHRCA2ALDH1A1HSP90AA1CYP1A2
SCHEMBL9892427 0.78 CA2 (0.70) TSHRCA2ALDH1A1HSP90AA1CYP1A2
2,6-Dichlorophenol SCHEMBL28437484 0.76 ALDH1A1 (0.65) TSHRCA2ALDH1A1HSP90AA1CYP1A2
SCHEMBL8387507 0.75 CA2 (0.46) TSHRCA2ALDH1A1HSP90AA1CYP1A2
2,6-Dichlorophenol SCHEMBL5578255 0.74 ALDH1A1 (0.44) TSHRALDH1A1HSP90AA1CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1998888-A1 APPARATUS FOR THERMALLY DEHALOGENATING HALOGENATED SUBSTANCES Forschungszentrum Karlsruhe GmbH (DE) 2008-12-10 EP disclosed
WO-2007112776-A1 APPARATUS FOR THERMALLY DEHALOGENATING HALOGENATED SUBSTANCES FORSCHUNGSZENTRUM KARLSRUHE GMBH (DE) 2007-10-11 WO disclosed