2,6-Dichlorophenol

2,6-Dichlorophenol

SCHEMBL5578255

O=S(=O)(Cl)Cl.Oc1c(Cl)cccc1Cl

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
TSHR P16473 5/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
CA1 P00915 1/20 0.41
ACHE P22303 1/20 0.41
HSP90AA1 P07900 1/20 0.39
DPP4 P27487 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39
HSD17B10 Q99714 2/20 0.38
IDO1 P14902 1/20 0.38
KDM4E B2RXH2 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
LMNA P02545 1/20 0.38
AKR1B1 P15121 1/20 0.38
TTR P02766 1/20 0.38
CYP3A4 P08684 1/20 0.38
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,6-Dichlorophenol SCHEMBL65234 0.86
2,6-Dichlorophenol SCHEMBL949095 0.83 TSHR (0.52) ALDH1A1TSHRMEN1KMT2ATDP1
2,6-Dichlorophenol SCHEMBL30790427 0.83 TSHR (0.52) ALDH1A1TSHRMEN1KMT2ATDP1
2,6-Dichlorophenol SCHEMBL10747747 0.83 TSHR (0.52) ALDH1A1TSHRMEN1KMT2ATDP1
2,6-Dichlorophenol SCHEMBL30257485 0.83 TSHR (0.52) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL27812266 0.81 ACLY (0.42) ALDH1A1TSHRMEN1KMT2ATDP1
2,6-Dichlorophenol SCHEMBL8986495 0.80 TSHR (0.50) ALDH1A1TSHRMEN1KMT2ATDP1
2,6-Dichlorophenol SCHEMBL28241861 0.79 ALDH1A1 (0.50) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL9540649 0.78 ACLY (0.43) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL9579955 0.78 TSHR (0.48) ALDH1A1TSHRMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070225344-A1 Sulfonamide derivatives to treat infection with hepatitis C virus WYETH 2007-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070225344-A1 Sulfonamide derivatives to treat infection with hepatitis C virus HCCS, HAVCR2, SULT2A1 ALDH1A1 907/4885TSHR 670/4885MEN1 2113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.