Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,6-Dichlorophenol SCHEMBL65234 | 0.86 | — | — | |
| 2,6-Dichlorophenol SCHEMBL949095 | 0.83 | TSHR (0.52) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| 2,6-Dichlorophenol SCHEMBL30790427 | 0.83 | TSHR (0.52) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| 2,6-Dichlorophenol SCHEMBL10747747 | 0.83 | TSHR (0.52) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| 2,6-Dichlorophenol SCHEMBL30257485 | 0.83 | TSHR (0.52) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| SCHEMBL27812266 | 0.81 | ACLY (0.42) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| 2,6-Dichlorophenol SCHEMBL8986495 | 0.80 | TSHR (0.50) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| 2,6-Dichlorophenol SCHEMBL28241861 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| SCHEMBL9540649 | 0.78 | ACLY (0.43) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| SCHEMBL9579955 | 0.78 | TSHR (0.48) | ALDH1A1TSHRMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225344-A1 | Sulfonamide derivatives to treat infection with hepatitis C virus | WYETH | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225344-A1 | Sulfonamide derivatives to treat infection with hepatitis C virus | HCCS, HAVCR2, SULT2A1 | ALDH1A1 907/4885TSHR 670/4885MEN1 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.