Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13319709 | 0.85 | NR3C1 (0.32) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL13995063 | 0.83 | CYP1A2 (0.43) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13995131 | 0.81 | NPC1 (0.35) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4079264 | 0.79 | DHFR (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4084177 | 0.79 | DHFR (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL13995130 | 0.78 | TRPA1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL13995094 | 0.78 | DHFR (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL13995118 | 0.78 | GPR84 (0.36) | RAB9ASMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL13995091 | 0.78 | DHFR (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL13995068 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957604-B1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-09-23 | — | — | EP | disclosed |
| US-8795847-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-08-05 | — | — | US | disclosed |
| US-8795847-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-08-05 | — | — | US | disclosed |
| US-8795847-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-08-05 | — | — | US | disclosed |
| US-20080303003-A1 | Novel Materials for Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
| US-20080303003-A1 | Novel Materials for Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
| EP-1957604-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007065550-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080303003-A1 | Novel Materials for Organic Electroluminescent Devices | ANXA2, ANXA3, ANXA1 | NPC1 3585/4885RAB9A 2952/4885SMN1; SMN2 3678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.