SCHEMBL5011802

SCHEMBL5011802

CCN(CC)c1ccc(C(c2ccc(NC(C)Cc3ccccc3)cc2C)c2ccc(NC(C)Cc3ccccc3)cc2C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
NPY1R P25929 1/20 0.43
NPY2R P49146 1/20 0.43
CNR2 P34972 5/20 0.40
NOX1 Q9Y5S8 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
L3MBTL1 Q9Y468 4/20 0.37
NPSR1 Q6W5P4 2/20 0.37
CNR1 P21554 1/20 0.37
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
POLB P06746 1/20 0.36
SIGMAR1 Q99720 4/20 0.36
HTT P42858 2/20 0.36
LMNA P02545 1/20 0.36
KDM4E B2RXH2 1/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5011774 0.91 MEN1 (0.45) MEN1KMT2ANPY1RNPY2RCNR2
SCHEMBL5011920 0.89 ALDH1A1 (0.44) MEN1KMT2ACNR2NPC1RAB9A
SCHEMBL5011838 0.86 MEN1 (0.53) MEN1KMT2ANPY1RNPY2RCNR2
SCHEMBL5010102 0.82 KMT2A (0.50) MEN1KMT2AL3MBTL1NPSR1ALDH1A1
SCHEMBL11289142 0.79 GRK6 (0.34) MEN1KMT2ACNR2NPC1RAB9A
SCHEMBL5011812 0.79 CNR2 (0.42) MEN1KMT2ANPY1RNPY2RCNR2
SCHEMBL5011808 0.77 TSHR (0.54) KMT2ACNR2CNR1ALDH1A1MAPT
SCHEMBL5009568 0.75 GAA (0.45) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL133593 0.75 S100B (0.49) MEN1KMT2ACNR2NOX1NPC1
SCHEMBL7952524 0.75 S100B (0.49) MEN1KMT2ACNR2NOX1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080311524-A1 Method For Making Negative-Working Heat-Sensitive Lithographic Printing Plate Precursor AGFA GRAPHICS N.V. (BE) 2008-12-18 US disclosed
US-20060078802-A1 Holographic storage medium SABIC INNOVATIVE PLASTICS IP B.V. 2006-04-13 US disclosed
EP-0239868-B1 PHOTOCHROMIC SYSTEM, LAYER PREPARED THEREOF AND ITS USE BASF Aktiengesellschaft (DE) 1989-12-27 EP disclosed
US-4857438-A Photochromic system and layers produced therewith BASF AKTIENGESELLSCHAFT (DE) 1989-08-15 US disclosed
EP-0239868-A1 Photochromic system, layer prepared thereof and its use BASF Aktiengesellschaft (DE) 1987-10-07 EP disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed