SCHEMBL5012665

SCHEMBL5012665

N#Cc1cc2ccccc2c(-c2ccccc2)c1C#N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE9A O76083 2/20 0.46
KDM4E B2RXH2 5/20 0.43
ALDH1A1 P00352 4/20 0.43
CLK1 P49759 1/20 0.43
DYRK1A Q13627 1/20 0.43
ALOX5 P09917 1/20 0.42
NCOA3 Q9Y6Q9 1/20 0.41
HSD17B10 Q99714 4/20 0.40
ALOX15 P16050 1/20 0.40
ADORA2A P29274 4/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
MAOA P21397 2/20 0.40
MAOB P27338 2/20 0.40
ADRA2A P08913 1/20 0.40
HTT P42858 1/20 0.40
SQOR Q9Y6N5 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16383984 0.85 ADORA1 (0.47) PDE9AKDM4ECLK1DYRK1ANCOA3
SCHEMBL16383982 0.84 CLK1 (0.39) PDE9AKDM4EALDH1A1CLK1DYRK1A
SCHEMBL28428018 0.83 SQOR (0.50) PDE9AKDM4EALDH1A1ALOX5NCOA3
SCHEMBL28345506 0.81 FASN (0.43) KDM4EALDH1A1CLK1DYRK1AALOX5
SCHEMBL16383955 0.81 CTSS (0.46) KDM4EALDH1A1SMN1; SMN2MAPTKMT2A
SCHEMBL16984847 0.81 ALDH1A1 (0.47) PDE9AKDM4EALDH1A1HSD17B10ALOX15
SCHEMBL16384089 0.81 CLK1 (0.37) PDE9AKDM4EALDH1A1CLK1DYRK1A
SCHEMBL29489130 0.80 MCL1 (0.47) KDM4ECLK1DYRK1ANCOA3ALOX15
SCHEMBL31457372 0.80 CLK1 (0.49) KDM4EALDH1A1CLK1DYRK1ANCOA3
SCHEMBL28869476 0.80 CLK1 (0.49) KDM4EALDH1A1CLK1DYRK1ANCOA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611175-B1 NAPHTHALOCYANINE COMPOUND, METHOD FOR PRODUCING SAME, AND USE THEREOF YAMAMOTO CHEMICALS INC (JP) 2022-02-09 EP disclosed
US-11174274-B2 Naphthalocyanine compound, method for producing same, and use thereof YAMAMOTO CHEMICALS, INC. (JP) 2021-11-16 US disclosed
US-20210107924-A1 NAPHTHALOCYANINE COMPOUND, METHOD FOR PRODUCING SAME, AND USE THEREOF YAMAMOTO CHEMICALS, INC. (JP) 2021-04-15 US disclosed
EP-3611175-A1 NAPHTHALOCYANINE COMPOUND, METHOD FOR PRODUCING SAME, AND USE THEREOF Yamamoto Chemicals, Inc. (JP) 2020-02-19 EP disclosed
CN-101149576-B Electrostatic charge developing toner, developer using the same, developer cartridge, and image forming apparatus FUJI XEROX CO LTD 2010-05-26 CN disclosed
CN-101149576-A Electrostatic charge developing toner, developer using the same, developer cartridge, and image forming apparatus FUJI XEROX CO LTD (JP) 2008-03-26 CN disclosed
US-20080070142-A1 Toner for electrostatic charge development, and developer for electrostatic charge development using the same, developer cartridge for electrostatic charge development and image forming apparatus FUJI XEROX CO., LTD. (JP) 2008-03-20 US disclosed
US-20080070142-A1 Toner for electrostatic charge development, and developer for electrostatic charge development using the same, developer cartridge for electrostatic charge development and image forming apparatus FUJI XEROX CO., LTD. (JP) 2008-03-20 US disclosed
US-20080070142-A1 Toner for electrostatic charge development, and developer for electrostatic charge development using the same, developer cartridge for electrostatic charge development and image forming apparatus FUJI XEROX CO., LTD. (JP) 2008-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210107924-A1 NAPHTHALOCYANINE COMPOUND, METHOD FOR PRODUCING SAME, AND USE THEREOF MRPS9, INTS9, RPL19 PDE9A 2630/4885KDM4E 3081/4885ALDH1A1 2361/4885
US-11174274-B2 Naphthalocyanine compound, method for producing same, and use thereof MRPS9, INTS9, RPL19 PDE9A 2630/4885KDM4E 3081/4885ALDH1A1 2361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.