Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5013397 | 0.87 | DRD2 (0.36) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL2092799 | 0.83 | MALT1 (0.34) | DRD2MEN1KMT2ALMNA | |
| SCHEMBL27645184 | 0.80 | DRD2 (0.48) | DRD2DRD4DRD3 | |
| SCHEMBL5013426 | 0.77 | RBP4 (0.40) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL2092243 | 0.76 | MALT1 (0.35) | DRD2 | |
| SCHEMBL5013395 | 0.71 | MEN1 (0.47) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL5016097 | 0.71 | KDM4E (0.44) | DRD2DRD4DRD3 | |
| SCHEMBL2092802 | 0.70 | MALT1 (0.34) | DRD2MEN1KMT2A | |
| SCHEMBL5011858 | 0.69 | DRD4 (0.44) | DRD2DRD4DRD3LMNA | |
| SCHEMBL5016095 | 0.68 | ALDH1A1 (0.43) | DRD2DRD4DRD3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |