Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 4/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016095 | 0.89 | ALDH1A1 (0.43) | MEN1KMT2AMAPTDRD4ALDH1A1 | |
| SCHEMBL5013401 | 0.86 | MEN1 (0.47) | MEN1KMT2ASIGMAR1MAPTDRD4 | |
| SCHEMBL2092375 | 0.83 | RPS6KB1 (0.43) | MAPTDRD4ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5013349 | 0.76 | KCNN4 (0.46) | DRD4ALDH1A1KDM4EDRD2DRD3 | |
| SCHEMBL5016096 | 0.75 | ALDH1A1 (0.43) | MEN1KMT2ADRD4ALDH1A1KDM4E | |
| SCHEMBL27645249 | 0.75 | MEN1 (0.48) | MEN1KMT2ASIGMAR1MAPTDRD4 | |
| SCHEMBL5013394 | 0.71 | DRD2 (0.36) | MEN1KMT2ASIGMAR1DRD4DRD2 | |
| SCHEMBL2092675 | 0.71 | MAPT (0.37) | MAPTKDM4EHTTSMN1; SMN2 | |
| SCHEMBL27645184 | 0.71 | DRD2 (0.48) | MAPTDRD4DRD2DRD3 | |
| SCHEMBL2092379 | 0.69 | RPS6KB1 (0.43) | MAPTDRD4ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |