Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5013426 | 0.89 | RBP4 (0.40) | GAALMNARBP4KDM4EALDH1A1 | |
| SCHEMBL2098701 | 0.85 | MGLL (0.35) | KDM4EALDH1A1MEN1KMT2AFAAH | |
| SCHEMBL27644470 | 0.84 | DRD2 (0.43) | GAALMNARBP4KDM4EALDH1A1 | |
| SCHEMBL2098162 | 0.77 | SCN10A (0.36) | TP53MEN1KMT2A | |
| SCHEMBL5013397 | 0.77 | DRD2 (0.36) | TP53MEN1KMT2ADRD2DRD4 | |
| SCHEMBL27665953 | 0.76 | KDM4E (0.52) | GAALMNARBP4KDM4EALDH1A1 | |
| SCHEMBL5013297 | 0.74 | GAA (0.48) | GAALMNATP53RBP4KDM4E | |
| SCHEMBL2098699 | 0.74 | HRH3 (0.34) | ALDH1A1FAAHSMN1; SMN2KCNN4 | |
| SCHEMBL5536579 | 0.72 | DRD4 (0.60) | GAALMNATP53KDM4EALDH1A1 | |
| SCHEMBL5016368 | 0.71 | CASP1 (0.38) | LMNAKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |