SCHEMBL5013670

SCHEMBL5013670

Brc1c(-c2ccccc2)c2cc3nc(cc4ccc(cc5nc(cc1[nH]2)C=C5)[nH]4)C=C3

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.54
▸ STAT1 P42224 1/20 0.54
▸ MAPK13 O15264 3/20 0.35
▸ GCGR P47871 3/20 0.35
▸ MAPK12 P53778 3/20 0.35
▸ MAPK11 Q15759 3/20 0.35
▸ MAPK14 Q16539 3/20 0.35
▸ ATM Q13315 1/20 0.35
▸ RXFP1 Q9HBX9 1/20 0.35
▸ NPC1 O15118 3/20 0.33
▸ RAB9A P51151 3/20 0.33
▸ GAA P10253 2/20 0.33
▸ CYP19A1 P11511 1/20 0.33
▸ PTGES O14684 1/20 0.32
▸ DHODH Q02127 1/20 0.32
▸ HPGD P15428 5/20 0.32
▸ SMN1; SMN2 Q16637 3/20 0.32
▸ LMNA P02545 2/20 0.32
▸ MAPT P10636 6/20 0.32
▸ ALDH1A1 P00352 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27937346 0.98 STAT3 (0.52) STAT3STAT1MAPK13GCGRMAPK12
SCHEMBL226837 0.91 STAT3 (0.59) STAT3STAT1MAPK13MAPK12MAPK11
SCHEMBL14054511 0.89 STAT3 (0.57) STAT3STAT1MAPK13MAPK12MAPK11
SCHEMBL6265476 0.89 STAT3 (0.57) STAT3STAT1MAPK13MAPK12MAPK11
SCHEMBL7762016 0.85 STAT3 (0.54) STAT3STAT1NPC1RAB9AGAA
SCHEMBL5067206 0.84 STAT3 (0.52) STAT3STAT1NPC1RAB9AGAA
SCHEMBL899162 0.84 STAT3 (0.52) STAT3STAT1MAPK13MAPK12MAPK11
SCHEMBL31499126 0.84 STAT3 (0.52) STAT3STAT1NPC1RAB9AGAA
SCHEMBL31435710 0.84 STAT3 (0.52) STAT3STAT1NPC1RAB9AGAA
SCHEMBL31435711 0.84 STAT3 (0.52) STAT3STAT1NPC1RAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899348-A Preparation method of novel photoelectric catalyst of covalent organic framework and photoelectric catalyst thereof 广东药科大学 2025-04-29 — — CN claimed
CN-119899348-B Preparation method of novel photoelectric catalyst of covalent organic framework and photoelectric catalyst thereof 广东药科大学 2025-09-30 — — CN disclosed
CN-119899348-A Preparation method of novel photoelectric catalyst of covalent organic framework and photoelectric catalyst thereof 广东药科大学 2025-04-29 — — CN disclosed
CN-119899348-A Preparation method of novel photoelectric catalyst of covalent organic framework and photoelectric catalyst thereof 广东药科大学 2025-04-29 — — CN disclosed
CN-109111913-B A kind of pair of transmitting cellulose base fluorescent material and its preparation method and application 中国科学院化学研究所 2019-10-01 — — CN disclosed
CN-109111913-A A kind of pair of transmitting cellulose base fluorescent material and its preparation method and application 中国科学院化学研究所 2019-01-01 — — CN disclosed
CN-105111426-A Quaternary ammonium salt functionalized porphyrin catalyst and preparation method thereof UNIV WUHAN TECH 2015-12-02 — — CN disclosed
CN-103664966-A Method for preparing asymmetric 5,15-bis(p-nitrophenyl)-10, 20-diphenyl porphyrin compound UNIV BEIJING TECHNOLOGY 2014-03-26 — — CN disclosed
US-7417142-B2 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, INC. (US) 2008-08-26 — — US disclosed
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2006-02-09 — — US disclosed
US-6951935-B2 Heteroatom-substituted porphyrins and methods for synthesis of same UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2005-10-04 — — US disclosed
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2005-06-09 — — US disclosed
CN-1194001-C Synthesis of monocrystal porphyrin UNIV TSINGHUA (CN) 2005-03-23 — — CN disclosed
US-20030236400-A1 Heteroatom-substituted porphyrins and methods for synthesis of same UNIVERSITY OF TENNESSEE RESEARCH CORPORATION 2003-12-25 — — US disclosed
CN-1403460-A Synthesis of monocrystal porphyrin UNIV TSINGHUA (CN) 2003-03-19 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes PPOX, HCCS, ICOSLG STAT3 3817/4885STAT1 4312/4885MAPK13 3435/4885
US-20030236400-A1 Heteroatom-substituted porphyrins and methods for synthesis of same PPOX, HMBS, UROD STAT3 4156/4885STAT1 3973/4885MAPK13 4347/4885
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same PPOX, PPIF, HMBS STAT3 2986/4885STAT1 3579/4885MAPK13 3982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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