SCHEMBL5013801

SCHEMBL5013801

O=NC(S)C(O)CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29429791 0.72 LMNA (0.53)
SCHEMBL2230381 0.71
SCHEMBL29409228 0.70 LMNA (0.50)
SCHEMBL13841279 0.69
SCHEMBL6699963 0.65 TDP1 (0.56)
SCHEMBL19921541 0.65
SCHEMBL242451 0.65
SCHEMBL23266184 0.65 LMNA (0.50)
SCHEMBL38654734 0.65 LMNA (0.58)
SCHEMBL10022040 0.65 LMNA (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3274001-A1 STERILISATION OF S-NITROSOTHIOLS Salupont Consulting Ltd. (GB) 2018-01-31 EP claimed
WO-2016156794-A1 STERILISATION OF S-NITROSOTHIOLS SALUPONT CONSULTING LTD (GB) 2016-10-06 WO claimed
EP-0914348-B1 POLYMERS FOR DELIVERING NITRIC OXIDE IN VIVO DUKE UNIVERSITY MEDICAL CT (US) 2002-06-12 EP claimed
EP-0914348-A1 POLYMERS FOR DELIVERING NITRIC OXIDE IN VIVO DUKE UNIVERSITY MEDICAL CENTER (US) 1999-05-12 EP claimed
WO-1998005689-A1 POLYMERS FOR DELIVERING NITRIC OXIDE IN VIVO DUKE UNIVERSITY MEDICAL CENTER (US) 1998-02-12 WO claimed
US-7417109-B2 Polymers for delivering nitric oxide in vivo DUKE UNIVERSITY (US) 2008-08-26 US disclosed
US-20070088435-A1 Novel polymers for delivering nitric oxide in vivo STAMLER JONATHAN S 2007-04-19 US disclosed
EP-1093468-B1 POLYMERS FOR DELIVERING NITRIC OXIDE IN VIVO UNIV DUKE (US) 2006-12-13 EP disclosed
US-7087709-B2 Polymers for delivering nitric oxide in vivo DUKE UNIVERSITY (US) 2006-08-08 US disclosed
US-20050220756-A1 Nitrosation of a organosulfur polymer; coating medical equipment such as tubes, catheters DUKE UNIVERSITY (US) 2005-10-06 US disclosed
US-6875840-B2 Polymers for delivering nitric oxide in vivo DUKE UNIVERSITY (US) 2005-04-05 US disclosed
US-20040132904-A1 Novel polymers for delivering nitric oxide in vivo DUKE UNIVERSITY 2004-07-08 US disclosed
WO-2002016320-A2 HIGH YIELD S-NITROSYLATION PROCESS SCIMED LIFE SYSTEMS, INC. (US) 2002-02-28 WO disclosed
US-20010020083-A1 Novel Polymers for Delivering nitric oxide in vivo STAMLER JONATHAN S (US) 2001-09-06 US disclosed
US-6232434-B1 MODIFIED POLYSACCHARIDES, CYCLODEXTRINS DUKE UNIVERSITY MEDICAL CENTER 2001-05-15 US disclosed
EP-1093468-A1 POLYMERS FOR DELIVERING NITRIC OXIDE IN VIVO DUKE UNIVERSITY MEDICAL CENTER (US) 2001-04-25 EP disclosed
WO-1999067296-A1 POLYMERS FOR DELIVERING NITRIC OXIDE IN VIVO DUKE UNIVERSITY MEDICAL CENTER (US) 1999-12-29 WO disclosed
EP-0914348-A1 POLYMERS FOR DELIVERING NITRIC OXIDE IN VIVO DUKE UNIVERSITY MEDICAL CENTER (US) 1999-05-12 EP disclosed
US-5770645-A THIOLATED NITROSYLATED POLYSACCHARIDE DUKE UNIVERSITY MEDICAL CENTER (US) 1998-06-23 US disclosed
WO-1998005689-A1 POLYMERS FOR DELIVERING NITRIC OXIDE IN VIVO DUKE UNIVERSITY MEDICAL CENTER (US) 1998-02-12 WO disclosed