SCHEMBL29409228

SCHEMBL29409228

O=N[C@H](O)[C@H](O)[C@H](O)CO.[N]

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
PDE4A P27815 1/20 0.41
USP2 O75604 1/20 0.38
SLCO1B1 Q9Y6L6 1/20 0.38
KDM4E B2RXH2 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29429791 0.97 LMNA (0.53) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL38654734 0.90 LMNA (0.58) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL2230381 0.80
Sorbitol SCHEMBL29468856 0.75 LMNA (0.69) LMNAL3MBTL1TDP1PDE4AUSP2
Mannitol SCHEMBL28979520 0.75 LMNA (0.69) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL23266184 0.74 LMNA (0.50) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL10022040 0.74 LMNA (0.50) LMNAL3MBTL1TDP1PDE4AUSP2
Mannitol SCHEMBL20594083 0.69 LMNA (1.00) LMNAL3MBTL1TDP1PDE4AUSP2
Adonitol SCHEMBL22572531 0.69 LMNA (0.83) LMNAL3MBTL1TDP1PDE4AUSP2
Mannitol SCHEMBL21837180 0.69 LMNA (1.00) LMNAL3MBTL1TDP1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146249-A1 ANTISENSE OLIGONUCLEOTIDES FOR TREATING A DISEASE OR CONDITION ASSOCIATED WITH AN ABNORMAL PROCESSING OF APP VICO THERAPEUTICS B.V. (NL) 2026-05-28 US disclosed
WO-2026099473-A1 OLIGONUCLEOTIDES WITH NEW INTERNUCLEOSIDE LINKAGE VICO THERAPEUTICS B.V. (NL) 2026-05-15 WO disclosed
EP-4713459-A2 ANTI-VISTA ANTIBODY RNA OR NUCLEIC ACID CONJUGATES (ARCS OR ANCS), COMPOSITIONS CONTAINING, AND THERAPEUTIC USE THEREOF LIFORDI IMMUNOTHERAPEUTICS, INC. (US) 2026-03-25 EP disclosed
EP-4702144-A1 ANTISENSE OLIGOMERS FOR TREATMENT OF CHRONIC KIDNEY DISEASE Sarepta Therapeutics, Inc. (US) 2026-03-04 EP disclosed
US-20260048076-A1 METHODS FOR DECREASING OR INHIBITING HUMAN L1 RETROTRANSPOSON RNA AND COMPOSITIONS FOR USE THEREIN ALTOS LABS, INC. (US) 2026-02-19 US disclosed
EP-4015631-B1 NOVEL PROCESSES FOR THE PRODUCTION OF OLIGONUCLEOTIDES GLAXOSMITHKLINE IP DEV LTD (GB) 2026-02-18 EP disclosed
US-20260014263-A1 PEPTIDE OLIGONUCLEOTIDE CONJUGATES SAREPTA THERAPEUTICS, INC. (US) 2026-01-15 US disclosed
EP-4674964-A1 RNA INTERFERENCE STRATEGIES TARGETING SMALL HEAT SHOCK PROTEIN B8 Universiteit Antwerpen (BE) 2026-01-07 EP disclosed
US-12502432-B2 Bicyclic peptide oligonucleotide conjugates SAREPTA THERAPEUTICS, INC. (US) 2025-12-23 US disclosed
US-20250382325-A1 DEPROTECTION PROCESSES AND CATION SCAVENGERS FOR USE IN THE SAME EXACTMER LTD (GB) 2025-12-18 US disclosed
WO-2022120410-A1 COMPOSITIONS AND METHODS FOR TREATING TARDBP ASSOCIATED DISEASES Perron Institute for Neurological and Translational Science Limited (AU) 2022-06-16 WO disclosed
US-11345915-B2 RNA modulating oligonucleotides with improved characteristics for the treatment of neuromuscular disorders VICO THERAPEUTICS B.V. (NL) 2022-05-31 US disclosed
CN-109415399-B Novel method for producing oligonucleotides 葛兰素史克知识产权开发有限公司 2022-05-24 CN disclosed
US-11338041-B2 Exon skipping oligomer conjugates for muscular dystrophy SAREPTA THERAPEUTICS, INC. (US) 2022-05-24 US disclosed
EP-3998339-A1 EXON SKIPPING COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY Sarepta Therapeutics, Inc. (US) 2022-05-18 EP disclosed
CN-107921092-B Peptide oligonucleotide conjugates 萨勒普塔医疗公司 2022-04-08 CN disclosed
EP-3728585-B1 NOVEL PROCESSES FOR THE PRODUCTION OF OLIGONUCLEOTIDES GLAXOSMITHKLINE IP DEV LTD (GB) 2022-03-16 EP disclosed
US-20220072143-A1 Peptide Oligonucleotide Conjugates JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2022-03-10 US disclosed
EP-3963077-A1 TREATMENT FOR SOD1 ASSOCIATED DISEASE Black Swan Pharmaceuticals, Inc. (US) 2022-03-09 EP disclosed
EP-3955966-A1 COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY Sarepta Therapeutics, Inc. (US) 2022-02-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11338041-B2 Exon skipping oligomer conjugates for muscular dystrophy SMN1; SMN2, UTRN, RBM17 LMNA 904/4885L3MBTL1 283/4885TDP1 827/4885
US-12502432-B2 Bicyclic peptide oligonucleotide conjugates MUSK, MTPN, TNNC1 LMNA 1927/4885L3MBTL1 116/4885TDP1 854/4885
US-20220072143-A1 Peptide Oligonucleotide Conjugates MYOF, MUSK, MTPN LMNA 3089/4885L3MBTL1 133/4885TDP1 879/4885
US-20260146249-A1 ANTISENSE OLIGONUCLEOTIDES FOR TREATING A DISEASE OR CONDITION ASSOCIATED WITH AN ABNORMAL PROCESSING OF APP APP, PSEN2, PSEN1 LMNA 69/4885L3MBTL1 270/4885TDP1 216/4885
US-20260014263-A1 PEPTIDE OLIGONUCLEOTIDE CONJUGATES SSU72, TNNC1, MUSK LMNA 906/4885L3MBTL1 34/4885TDP1 481/4885
US-20260048076-A1 METHODS FOR DECREASING OR INHIBITING HUMAN L1 RETROTRANSPOSON RNA AND COMPOSITIONS FOR USE THEREIN POT1, FBL, HNRNPA1 LMNA 23/4885L3MBTL1 29/4885TDP1 22/4885
US-20250382325-A1 DEPROTECTION PROCESSES AND CATION SCAVENGERS FOR USE IN THE SAME ACMSD, DCTD, MSR1 LMNA 56/4885L3MBTL1 2633/4885TDP1 1655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.