Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | LPL | P06858 | 6/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14092907 | 0.81 | GPR3 (0.40) | GPR3LPLLIPG | |
| SCHEMBL27684714 | 0.81 | GPR3 (0.44) | GPR3LPLLIPGESR1ADRA2A | |
| SCHEMBL27944146 | 0.77 | GPR3 (0.63) | GPR3LPLLIPGESR1ADRA2A | |
| SCHEMBL5012391 | 0.75 | CYP1B1 (0.40) | GPR3CYP1B1LIPGNPSR1KDM4E | |
| SCHEMBL8987635 | 0.72 | GPR3 (0.57) | GPR3LPLLIPGESR1ADRA2A | |
| SCHEMBL27744086 | 0.71 | GPR3 (0.41) | GPR3LPLLIPGESR1ADRA2A | |
| SCHEMBL4737345 | 0.70 | GPR3 (0.54) | GPR3LPLLIPGESR1ADRA2A | |
| SCHEMBL5011003 | 0.70 | MAPK1 (0.65) | CYP1B1NPSR1KDM4EALDH1A1TP53 | |
| SCHEMBL728651 | 0.70 | RAB9A (0.41) | GPR3ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL2403161 | 0.70 | ESR1 (0.47) | ESR1ADRA2AADORA3TACR2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |
| CN-1950382-A | Organosilanes, process for production of the same, and use thereof | SHARP KK (JP) | 2007-04-18 | — | — | CN | disclosed |