Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.43 |
| ▸ | MYLK | Q15746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | SELL | P14151 | 1/20 | 0.42 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | SELE | P16581 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278609 | 0.84 | ALOX5 (0.49) | MEN1MAPTKMT2ATDP1 | |
| SCHEMBL2221249 | 0.83 | ALOX15 (0.43) | PTPN1PRKCEMYLKMEN1ALDH1A1 | |
| SCHEMBL278588 | 0.82 | BCL2 (0.62) | PTPN1MEN1KMT2AHIF1AHSD17B10 | |
| SCHEMBL9059697 | 0.80 | HSPA5 (0.47) | PTPN1PRKCEMYLKMEN1ALDH1A1 | |
| SCHEMBL5532933 | 0.79 | HMGCR (0.42) | PTPN1PRKCEMYLKMEN1ALDH1A1 | |
| SCHEMBL8072029 | 0.76 | GABRA1 (0.46) | PRKCEMYLKMEN1ALDH1A1MAPT | |
| SCHEMBL10743686 | 0.74 | TYR (0.56) | MEN1MAPTKMT2ATDP1 | |
| SCHEMBL5517885 | 0.73 | TYR (0.59) | MEN1MAPTKMT2ATDP1 | |
| SCHEMBL2220478 | 0.73 | SELL (0.50) | PRKCEMYLKMEN1ALDH1A1MAPT | |
| Propane SCHEMBL2218962 | 0.72 | SELL (0.43) | PRKCEMYLKMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387152-A | Light-sensitive mixture and copying material prepared therefrom, and process for the preparation of a printing form from the copying material | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-06-07 | — | — | US | claimed |
| JP-8311141-A | — | — | None | — | — | JP | disclosed |
| US-20080070086-A1 | Phase-Separated Polymer Electrolyte Membrane, Electrode - Phase-Separated Polymer Electrolyte Membrane Joint Using Same, Method for Manufacture Thereof, and Fuel Cell Using Same | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2008-03-20 | — | — | US | disclosed |
| EP-1845573-A1 | PHASE SEPARATION TYPE POLYMER ELECTROLYTE FILM, ELECTRODE/PHASE SEPARATION TYPE POLYMER ELECTROLYTE FILM ASSEMBLY EMPLOYING THE SAME, PROCESSES FOR PRODUCING THE SAME, AND FUEL CELL EMPLOYING THE SAME | Hitachi Chemical Co., Ltd. (JP) | 2007-10-17 | — | — | EP | disclosed |
| EP-1352888-B1 | Hydroxymethyl-substituted polyfunctional phenols | HONSHU CHEMICAL IND (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-6906226-B2 | Hydroxymethyl-substituted polyfunctional phenols | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-06-14 | — | — | US | disclosed |
| US-6906130-B2 | Inverted novolac resin-type insulation binder | GEORGIA-PACIFIC RESINS, INC. (US) | 2005-06-14 | — | — | US | disclosed |
| US-20040082713-A1 | Inverted novolac resin-type insulation binder | GEORGIA-PACIFIC RESINS, INC. | 2004-04-29 | — | — | US | disclosed |
| US-20030204117-A1 | Hydroxymethyl-substituted polyfunctional phenols | HONSHU, CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-10-30 | — | — | US | disclosed |
| EP-1352888-A1 | Hydroxymethyl-substituted polyfunctional phenols | Honshu Chemical Industry Co., Ltd. (JP) | 2003-10-15 | — | — | EP | disclosed |
| JP-H08311141-A | RESOL TYPE PHENOLIC RESIN AND COATING THEREFROM | KISHIMOTO AKIRA | 1996-11-26 | — | — | JP | disclosed |
| US-5371140-A | Catalytic polymerization of phenol-formaldehyde using alkali metal base as catalyst and urea as free aldehyde scavanger; scavanging, neutralizing basic catalyst | GEORGIA-PACIFIC RESINS, INC. (US) | 1994-12-06 | — | — | US | disclosed |
| US-4028367-A | REACTING PHENOL WITH FORMALDEHYDE, DIHYDROXYDIPHENYLMETHANES PRESENT TO INHIBIT CRYSTAL FORMATION | MONSANTO COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-3956205-A | High efficiency aqueous resole solutions being stable to crystallization and emulsifiable with method of manufacture | MONSANTO COMPANY (US) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030204117-A1 | Hydroxymethyl-substituted polyfunctional phenols | TET1, TET3, TET2 | PTPN1 1364/4885PRKCE 4760/4885MYLK 4159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.