Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | XBP1 | P17861 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL800921 | 0.88 | PPARA (0.49) | ALDH1A1NPSR1HPGDHTTLMNA | |
| SCHEMBL1661413 | 0.85 | ALDH1A1 (0.51) | ALDH1A1NPSR1HPGDHTTLMNA | |
| SCHEMBL22648562 | 0.82 | CTSK (0.43) | ALDH1A1HTTLMNATSHRHSD17B10 | |
| SCHEMBL5014111 | 0.82 | CTSS (0.43) | ALDH1A1NPSR1HPGDHTTLMNA | |
| SCHEMBL10045812 | 0.81 | MAPT (0.60) | NPSR1KMT2AMEN1MAPTKLK5 | |
| SCHEMBL14737594 | 0.78 | KMT2A (0.44) | ALDH1A1LMNATSHRHSD17B10KMT2A | |
| SCHEMBL15214455 | 0.78 | GAA (0.36) | TSHRHSD17B10KMT2AKLK5CTSS | |
| SCHEMBL800495 | 0.78 | KMT2A (0.44) | ALDH1A1LMNATSHRHSD17B10KMT2A | |
| SCHEMBL800927 | 0.76 | LMNA (0.39) | ALDH1A1LMNATSHRHSD17B10KMT2A | |
| SCHEMBL22648564 | 0.74 | LMNA (0.43) | ALDH1A1NPSR1HPGDHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009942-A1 | HETEROAROMATIC-BASED PEPTIDE MACROCYCLES AS G-QUADRUPLEX LIGANDS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-01-24 | — | — | WO | disclosed |