Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14776447 | 0.71 | NPSR1 (0.54) | LMNANPSR1ALDH1A1KMT2AMCOLN3 | |
| SCHEMBL5012240 | 0.69 | HSD11B1 (0.41) | NPSR1GAAALDH1A1MEN1KMT2A | |
| SCHEMBL9495400 | 0.67 | NPSR1 (0.45) | LMNANPSR1GAAALDH1A1KMT2A | |
| SCHEMBL17083743 | 0.67 | SLC18A3 (0.39) | LMNAKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL23967443 | 0.65 | ALDH1A1 (0.65) | LMNANPSR1KDM4EALDH1A1MEN1 | |
| SCHEMBL2653818 | 0.65 | ALDH1A1 (0.65) | LMNANPSR1KDM4EALDH1A1MEN1 | |
| SCHEMBL30987468 | 0.65 | ALDH1A1 (0.65) | LMNANPSR1KDM4EALDH1A1MEN1 | |
| SCHEMBL11088410 | 0.65 | NPSR1 (0.50) | NPSR1ALDH1A1MEN1KMT2AMCOLN3 | |
| Bicarbonate SCHEMBL14811674 | 0.64 | ALDH1A1 (0.58) | LMNANPSR1KDM4EGAAALDH1A1 | |
| SCHEMBL6763525 | 0.63 | CES2 (0.46) | NPSR1GAAALDH1A1MCOLN3CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249146-A1 | Imidazole and Thioazole Derivatives as Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2008-10-09 | — | — | US | disclosed |
| EP-1773331-A1 | IMIDAZOLE AND THIAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006008556-A1 | IMIDAZOLE AND THIAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249146-A1 | Imidazole and Thioazole Derivatives as Antiviral Agents | IRF3, HAVCR2, ZC3HAV1 | LMNA 4527/4885NPSR1 3815/4885KDM4E 2816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.