Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014179 | 0.69 | LMNA (0.49) | CES2MEN1KMT2ANPSR1GAA | |
| SCHEMBL3033378 | 0.69 | HSD11B1 (0.41) | HSD11B1IL4I1NPSR1GRM5 | |
| SCHEMBL28623484 | 0.69 | HPGD (0.40) | HSD11B1CES2GAAALOX15HPGD | |
| SCHEMBL17083743 | 0.67 | SLC18A3 (0.39) | HSD11B1CES2MEN1KMT2AATM | |
| SCHEMBL14776447 | 0.65 | NPSR1 (0.54) | CES2KMT2ANPSR1HPGDALDH1A1 | |
| SCHEMBL19923636 | 0.64 | ALDH1A1 (0.43) | HSD11B1MEN1KMT2ANPSR1GAA | |
| SCHEMBL29590229 | 0.64 | GRM4 (0.48) | HSD11B1MEN1KMT2AGAAHPGD | |
| SCHEMBL23004922 | 0.62 | OPRM1 (0.49) | HSD11B1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL31252781 | 0.62 | MTR (0.59) | MEN1KMT2AGAAALOX15HPGD | |
| SCHEMBL30278373 | 0.62 | OPRM1 (0.49) | HSD11B1MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249146-A1 | Imidazole and Thioazole Derivatives as Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2008-10-09 | — | — | US | disclosed |
| CN-1997366-A | Imidazole and thiazole derivatives as antiviral agents | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-07-11 | — | — | CN | disclosed |
| EP-1773331-A1 | IMIDAZOLE AND THIAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006008556-A1 | IMIDAZOLE AND THIAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249146-A1 | Imidazole and Thioazole Derivatives as Antiviral Agents | IRF3, HAVCR2, ZC3HAV1 | HSD11B1 924/4885CES2 1424/4885IL4I1 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.