Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 20/20 | 0.47 |
| ▸ | TDO2 | P48775 | 20/20 | 0.47 |
| ▸ | IDO2 | Q6ZQW0 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27512146 | 0.77 | MEN1 (0.38) | IDO1 | |
| SCHEMBL27998221 | 0.76 | GPR84 (0.38) | IDO1 | |
| SCHEMBL30863941 | 0.76 | ADRA2A (0.35) | IDO1TDO2 | |
| Hydrochloric Acid SCHEMBL27998010 | 0.75 | GPR84 (0.37) | IDO1 | |
| SCHEMBL2721766 | 0.74 | — | — | |
| SCHEMBL31182065 | 0.74 | — | — | |
| SCHEMBL5016076 | 0.73 | GPR84 (0.30) | — | |
| SCHEMBL27998222 | 0.73 | — | — | |
| SCHEMBL4347870 | 0.72 | MAPT (0.42) | — | |
| Hydrochloric Acid SCHEMBL27998019 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419962-B2 | 3,6-bicyclolides | ENANTA PHARMACEUTICALS, INC. (US) | 2008-09-02 | — | — | US | disclosed |
| US-20060142214-A1 | 3,6-bicyclolides | ENANTA PHARMACEUTICALS, INC. | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142214-A1 | 3,6-bicyclolides | ABCB11, CYP2B6, CYP3A7 | IDO1 1074/4885TDO2 2545/4885IDO2 1338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.