Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2683313 | 0.82 | CYP1A2 (0.37) | LMNAGABRA1GABRB2 | |
| SCHEMBL5015100 | 0.81 | POLB (0.49) | GABRA1ALOX15GABRB2POLBGAA | |
| SCHEMBL5022865 | 0.77 | MAPK1 (0.34) | GABRA1ALOX15ALOX12GABRB2POLB | |
| SCHEMBL5022863 | 0.76 | CYP1A2 (0.33) | GABRA1GABRB2 | |
| SCHEMBL5015066 | 0.76 | ALDH1A1 (0.34) | GABRA1GABRB2 | |
| SCHEMBL14924905 | 0.74 | LMNA (0.41) | LMNAGABRA1GABRB1GABRB2POLB | |
| SCHEMBL11422616 | 0.74 | LMNA (0.41) | LMNAGABRA1GABRB1GABRB2POLB | |
| SCHEMBL5015048 | 0.73 | SLC6A4 (0.36) | — | |
| SCHEMBL18757899 | 0.70 | HTR2A (0.51) | — | |
| SCHEMBL15031067 | 0.70 | GABRA1 (0.39) | LMNAGABRA1GABRB1GABRB2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |