Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.55 |
| ▸ | ERN1 | O75460 | 4/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28866383 | 0.87 | ESR1 (0.58) | ESR1ESR2ERN1HSD17B1HSD17B2 | |
| SCHEMBL5023242 | 0.80 | PDE4A (0.44) | HSD17B1HSD17B2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7049899 | 0.79 | GRIN2D (0.49) | ESR1ESR2ERN1HSD17B1HSD17B2 | |
| SCHEMBL1803539 | 0.78 | ABCG2 (0.54) | ERN1CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL5016685 | 0.77 | CFD (0.46) | ESR1ESR2ERN1KDM4EMEN1 | |
| SCHEMBL3010060 | 0.77 | HSD17B1 (0.64) | ESR1ESR2ERN1HSD17B1HSD17B2 | |
| SCHEMBL10950376 | 0.77 | PLAU (0.50) | ESR2ERN1HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL11430028 | 0.76 | ESR2 (0.65) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL5302383 | 0.76 | ESR2 (0.81) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL30944686 | 0.76 | ESR2 (0.81) | ESR1ESR2HSD17B1HSD17B2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449608-B2 | Naphthol derivative and charge control agent comprising the same | UENO FINE CHEMICALS INDUSTRY, LTD. (JP) | 2008-11-11 | — | — | US | disclosed |
| CN-1289468-C | Naphthol derivative and charge control agent comprising the same | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2006-12-13 | — | — | CN | disclosed |
| CN-1217940-C | Naphthol derivatives | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2005-09-07 | — | — | CN | disclosed |
| US-20050119487-A1 | Naphthol derivative and charge control agent comprising the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2005-06-02 | — | — | US | disclosed |
| CN-1617851-A | Naphthol derivative and charge control agent comprising the same | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2005-05-18 | — | — | CN | disclosed |
| EP-1462440-A1 | NAPHTHOL DERIVATIVE AND CHARGE CONTROL AGENT COMPRISING THE SAME | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 2004-09-29 | — | — | EP | disclosed |
| CN-1386120-A | Naphthol derivatives | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2002-12-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119487-A1 | Naphthol derivative and charge control agent comprising the same | CECR2, PEF1, NAP1L1 | ESR1 2983/4885ESR2 3607/4885ERN1 2537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.