Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1050405 | 0.86 | LPAR3 (0.53) | ALDH1A1HSD17B10CYP3A4LPAR2LPAR3 | |
| SCHEMBL28359216 | 0.86 | LPAR3 (0.53) | ALDH1A1HSD17B10CYP3A4LPAR2LPAR3 | |
| SCHEMBL28355615 | 0.86 | LPAR3 (0.53) | ALDH1A1HSD17B10CYP3A4LPAR2LPAR3 | |
| SCHEMBL1044782 | 0.86 | LPAR3 (0.53) | ALDH1A1HSD17B10CYP3A4LPAR2LPAR3 | |
| SCHEMBL28359116 | 0.86 | LPAR3 (0.53) | ALDH1A1HSD17B10CYP3A4LPAR2LPAR3 | |
| SCHEMBL5015029 | 0.86 | LPAR3 (0.44) | ALDH1A1HSD17B10CYP3A4LPAR2LPAR3 | |
| SCHEMBL1050408 | 0.86 | LPAR3 (0.53) | ALDH1A1HSD17B10CYP3A4LPAR2LPAR3 | |
| SCHEMBL6691428 | 0.86 | LPAR3 (0.53) | ALDH1A1HSD17B10CYP3A4LPAR2LPAR3 | |
| SCHEMBL252445 | 0.83 | LPAR3 (0.50) | ALDH1A1HSD17B10CYP3A4LPAR2LPAR3 | |
| SCHEMBL11413278 | 0.82 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CYP3A4TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432089-B1 | Lubricating oil compositions | CIBA GEIGY AG (CH) | 1996-09-04 | — | — | EP | claimed |
| EP-3397740-A1 | LUBRICATING OIL COMPOSITION FOR DIESEL ENGINES | SHELL INTERNATIONAL RESEARCH MAATSCHAPPIJ B.V. (NL) | 2018-11-07 | — | — | EP | disclosed |
| WO-2017114836-A1 | LUBRICATING OIL COMPOSITION FOR DIESEL ENGINES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2017-07-06 | — | — | WO | disclosed |