Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | HTR7 | P34969 | 4/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27645227 | 0.86 | SIGMAR1 (0.49) | SIGMAR1NPC1MEN1RAB9AKMT2A | |
| SCHEMBL5063380 | 0.84 | RAB9A (0.67) | SIGMAR1NPC1MEN1RAB9AKMT2A | |
| SCHEMBL2095137 | 0.75 | MAPT (0.48) | NPC1MEN1RAB9AKMT2AHTR1A | |
| SCHEMBL2091149 | 0.73 | SMN1; SMN2 (0.68) | NPC1RAB9AMAPTL3MBTL1LMNA | |
| SCHEMBL5063385 | 0.72 | RAB9A (0.67) | NPC1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL8092982 | 0.72 | SIGMAR1 (0.85) | SIGMAR1MEN1KMT2ACCR3 | |
| SCHEMBL5015038 | 0.72 | RAB9A (0.50) | NPC1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL5015059 | 0.71 | SMN1; SMN2 (0.51) | NPC1RAB9AMAPTL3MBTL1LMNA | |
| SCHEMBL2091074 | 0.70 | MAPT (0.40) | NPC1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL5015014 | 0.70 | MAPT (0.43) | NPC1MEN1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |