Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015016 | 0.90 | MAPT (0.43) | MAPTNPC1MEN1RAB9AKMT2A | |
| SCHEMBL27666179 | 0.84 | RAB9A (0.62) | MAPTNPC1MEN1RAB9AKMT2A | |
| SCHEMBL5063380 | 0.80 | RAB9A (0.67) | MAPTNPC1MEN1RAB9AKMT2A | |
| SCHEMBL2091074 | 0.80 | MAPT (0.40) | MAPTNPC1MEN1RAB9AKMT2A | |
| SCHEMBL2095137 | 0.78 | MAPT (0.48) | MAPTNPC1MEN1RAB9AKMT2A | |
| SCHEMBL5015098 | 0.70 | SIGMAR1 (0.50) | MAPTNPC1MEN1RAB9AKMT2A | |
| SCHEMBL2091149 | 0.69 | SMN1; SMN2 (0.68) | MAPTNPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL2091076 | 0.69 | MAPT (0.40) | MAPTNPC1MEN1RAB9AKMT2A | |
| SCHEMBL5013359 | 0.69 | MEN1 (0.52) | MAPTNPC1MEN1RAB9AKMT2A | |
| SCHEMBL2098417 | 0.69 | CTSV (0.41) | MAPTNPC1RAB9ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |