SCHEMBL5015155

SCHEMBL5015155

CN(C)c1ccc(S(=O)(=O)C(F)(F)C(F)(F)S(=O)(=O)O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.43
ALOX15 P16050 4/20 0.43
HSD17B10 Q99714 3/20 0.43
HPGD P15428 2/20 0.43
KDM4E B2RXH2 1/20 0.43
TDP1 Q9NUW8 3/20 0.41
MAPT P10636 3/20 0.41
LMNA P02545 2/20 0.41
MAPK1 P28482 1/20 0.41
GFER P55789 1/20 0.41
MCL1 Q07820 1/20 0.41
CA9 Q16790 3/20 0.40
CA12 O43570 2/20 0.40
CA2 P00918 2/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
POLB P06746 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH3A1 P30838 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5017174 0.78 CA1 (0.44) ALDH1A1MAPK1CA9CA12CA2
SCHEMBL5014762 0.76 TSHR (0.48) ALDH1A1HSD17B10TDP1CA9CA12
SCHEMBL9332724 0.74 ALOX15 (0.39) ALDH1A1ALOX15HSD17B10HPGDKDM4E
SCHEMBL23784485 0.74 ALDH1A1 (0.52) ALDH1A1ALOX15HSD17B10HPGDKDM4E
SCHEMBL23784598 0.74 ALDH1A1 (0.52) ALDH1A1ALOX15HSD17B10HPGDKDM4E
SCHEMBL1134428 0.73 ALDH1A1 (0.55) ALDH1A1ALOX15HSD17B10HPGDKDM4E
Trifluoromethanesulfonic Acid SCHEMBL6423653 0.73 ALDH1A1 (0.58) ALDH1A1ALOX15HSD17B10HPGDKDM4E
SCHEMBL24386189 0.72 ALDH1A1 (0.50) ALDH1A1ALOX15HSD17B10HPGDKDM4E
Trifluoromethanesulfonic Acid SCHEMBL4575017 0.71 ALDH1A1 (0.41) ALDH1A1ALOX15HSD17B10HPGDKDM4E
Hydrochloric Acid SCHEMBL28095718 0.71 ALDH1A1 (0.53) ALDH1A1ALOX15HSD17B10HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008009815-A2 METHOD FOR PREPARING AROMATIC SULFONATES INSTITUT NATIONAL POLYTECHNIQUE DE GRENOBLE (FR) 2008-01-24 WO disclosed