Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014762 | 0.82 | TSHR (0.48) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL19498735 | 0.81 | NAMPT (0.42) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL571463 | 0.81 | MMP2 (0.43) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9489943 | 0.79 | CA1 (0.42) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5015155 | 0.78 | ALDH1A1 (0.43) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL8849931 | 0.78 | HSD11B1 (0.43) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL7937243 | 0.76 | ALDH1A1 (0.52) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9270354 | 0.74 | CA2 (0.45) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9457858 | 0.74 | CA2 (0.45) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4319799 | 0.74 | AKR1B1 (0.39) | PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009815-A2 | METHOD FOR PREPARING AROMATIC SULFONATES | INSTITUT NATIONAL POLYTECHNIQUE DE GRENOBLE (FR) | 2008-01-24 | — | — | WO | disclosed |