Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL6423653 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HSD17B10ALOX15TSHRGAA | |
| Trifluoromethanesulfonic Acid SCHEMBL1005215 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HSD17B10ALOX15TSHRHPGD | |
| Trifluoromethanesulfonic Acid SCHEMBL8592503 | 0.80 | CA2 (0.40) | ALDH1A1HSD17B10ALOX15TSHRGAA | |
| Trifluoromethanesulfonic Acid SCHEMBL6248784 | 0.79 | CA2 (0.42) | ALDH1A1GAACA2CA1MEN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL1377208 | 0.78 | CHRM5 (0.59) | ALDH1A1HSD17B10ALOX15TSHRGAA | |
| Trifluoromethanesulfonic Acid SCHEMBL1455936 | 0.77 | CA2 (0.41) | ALDH1A1GAACA2CA1MEN1 | |
| SCHEMBL543678 | 0.77 | ALDH1A1 (0.69) | ALDH1A1HSD17B10ALOX15TSHRGAA | |
| Trifluoromethanesulfonic Acid SCHEMBL3684082 | 0.76 | CA1 (0.38) | ALDH1A1CA2CA1MEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL28173684 | 0.76 | LMNA (0.43) | ALDH1A1HSD17B10ALOX15HPGDMAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL5456592 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TSHRGAAMAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10098974-B2 | Catalytic radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2018-10-16 | — | — | US | disclosed |
| US-20150132223-A1 | Catalytic Radiofluorination | THE GENERAL HOSPITAL CORPORATION | 2015-05-14 | — | — | US | disclosed |
| US-8900550-B2 | Catalytic radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2014-12-02 | — | — | US | disclosed |
| US-20130115168-A1 | Catalytic Radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2013-05-09 | — | — | US | disclosed |
| US-8257680-B1 | Catalytic radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2012-09-04 | — | — | US | disclosed |
| US-20120207677-A1 | CATALYTIC RADIOFLUORINATION | THE GENERAL HOSPITAL CORPORATION | 2012-08-16 | — | — | US | disclosed |
| WO-2008022319-A2 | CATALYTIC RADIOFLUORINATION | THE GENERAL HOSPITAL CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130115168-A1 | Catalytic Radiofluorination | ARSA, STS, KCNK18 | ALDH1A1 1308/4885HSD17B10 2541/4885ALOX15 4355/4885 |
| US-10098974-B2 | Catalytic radiofluorination | ARSA, STS, KCNK18 | ALDH1A1 1308/4885HSD17B10 2541/4885ALOX15 4355/4885 |
| US-20150132223-A1 | Catalytic Radiofluorination | ARSA, KCNK18, STS | ALDH1A1 1178/4885HSD17B10 1196/4885ALOX15 3760/4885 |
| US-20120207677-A1 | CATALYTIC RADIOFLUORINATION | ARSA, STS, KCNK18 | ALDH1A1 1308/4885HSD17B10 2541/4885ALOX15 4355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.