Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.67 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.64 |
| ▸ | PPARG | P37231 | 7/20 | 0.64 |
| ▸ | PPARD | Q03181 | 7/20 | 0.64 |
| ▸ | PPARA | Q07869 | 7/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | FABP4 | P15090 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | TLR2 | O60603 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.64 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nonanoate SCHEMBL27628803 | 0.98 | GPR84 (0.68) | AKR1B1GPR84PPARGPPARDPPARA | |
| Heptanoate SCHEMBL9706299 | 0.98 | GPR84 (0.68) | AKR1B1GPR84PPARGPPARDPPARA | |
| Stearic Acid SCHEMBL8132485 | 0.98 | GPR84 (0.68) | AKR1B1GPR84PPARGPPARDPPARA | |
| Octanoic Acid SCHEMBL7413713 | 0.98 | GPR84 (0.68) | AKR1B1GPR84PPARGPPARDPPARA | |
| Palmitic Acid SCHEMBL27955991 | 0.98 | GPR84 (0.68) | AKR1B1GPR84PPARGPPARDPPARA | |
| Valeric Acid SCHEMBL454061 | 0.94 | ALDH1A1 (0.61) | AKR1B1GPR84PPARGPPARDPPARA | |
| Adipic Acid SCHEMBL11807980 | 0.94 | ALDH1A1 (0.67) | AKR1B1GPR84PPARGPPARDPPARA | |
| Dodecanoate SCHEMBL28964764 | 0.93 | GPR84 (0.61) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexanoate SCHEMBL27507375 | 0.93 | AKR1B1 (0.57) | AKR1B1GPR84PPARGPPARDPPARA | |
| Butyric Acid SCHEMBL3939998 | 0.92 | ALDH1A1 (0.58) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761478-B1 | AN ISOLATED ATOMOXETINE IMPURITY, PROCESSES FOR THE PREPARATION OF ATOMOXETINE IMPURITIES AND THEIR USE AS REFERENCE STANDARDS | TEVA PHARM FINE CHEMICALS SRL (IT) | 2008-09-03 | — | — | EP | claimed |
| US-7378553-B2 | Isolated atomoxetine impurity, processes for the preparation of atomoxetine impurities and their use as reference standards | TEVA PHARMACEUTICAL FINE CHEMICALS S.R.L. (IT) | 2008-05-27 | — | — | US | claimed |
| EP-1761478-A2 | AN ISOLATED ATOMOXETINE IMPURITY, PROCESSES FOR THE PREPARATION OF ATOMOXETINE IMPURITIES AND THEIR USE AS REFERENCE STANDARDS | Teva Pharmaceutical Fine Chemicals S.R.L. (IT) | 2007-03-14 | — | — | EP | claimed |
| WO-2006004979-A2 | AN ISOLATED ATOMOXETINE IMPURITY, PROCESSES FOR THE PREPARATION OF ATOMOXETINE IMPURITIES AND THEIR USE AS REFERENCE STANDARDS | TEVA PHARMACEUTICAL FINE CHEMICALS S.R.L. (IT) | 2006-01-12 | — | — | WO | claimed |
| US-20060009532-A1 | Isolated atomoxetine impurity, processes for the preparation of atomoxetine impurities and their use as reference standards | TEVA PHARMCEUTICALS USA, INC. | 2006-01-12 | — | — | US | claimed |
| WO-2004052883-A2 | PROCESS FOR THE SEPARATION OF ENANTIOMERS | HONEYWELL INTERNATIONAL INC. (US) | 2004-06-24 | — | — | WO | claimed |
| CN-102471453-B | Polycarbonates having a scratch-resistant coating and having high transparency, method for the production thereof, and use thereof | BASF COATINGS GMBH | 2014-09-17 | — | — | CN | disclosed |
| EP-1761478-B1 | AN ISOLATED ATOMOXETINE IMPURITY, PROCESSES FOR THE PREPARATION OF ATOMOXETINE IMPURITIES AND THEIR USE AS REFERENCE STANDARDS | TEVA PHARM FINE CHEMICALS SRL (IT) | 2008-09-03 | — | — | EP | disclosed |
| US-7378553-B2 | Isolated atomoxetine impurity, processes for the preparation of atomoxetine impurities and their use as reference standards | TEVA PHARMACEUTICAL FINE CHEMICALS S.R.L. (IT) | 2008-05-27 | — | — | US | disclosed |
| US-7355078-B2 | Processes for the preparation of tomoxetine | TEVA PHARMACEUTICAL FINE CHEMICALS S.R.L. (IT) | 2008-04-08 | — | — | US | disclosed |
| CN-101151257-A | Process for production of 1-(3-(2-(1-benzothiophen-5-yl)-ethoxy)propyl)azetidin-3-ol or salts thereof | TOYAMA CHEMICAL CO LTD (JP) | 2008-03-26 | — | — | CN | disclosed |
| CN-1946678-A | Isolated atomoxetine impurity, processes for the preparation of atomoxetine impurities and their use as reference standards | TEVA PHARM FINE CHEMICALS SRL (IT) | 2007-04-11 | — | — | CN | disclosed |
| EP-1761478-A2 | AN ISOLATED ATOMOXETINE IMPURITY, PROCESSES FOR THE PREPARATION OF ATOMOXETINE IMPURITIES AND THEIR USE AS REFERENCE STANDARDS | Teva Pharmaceutical Fine Chemicals S.R.L. (IT) | 2007-03-14 | — | — | EP | disclosed |
| CN-1442410-A | Improved method of preparing secnidazole | GEN CHEMICAL LAB LTD (IN) | 2003-09-17 | — | — | CN | disclosed |
| CN-1120828-C | Process for purifying pentafluoroethane | ZHEJIANG PROV CHEMICAL ENGINEE (CN) | 2003-09-10 | — | — | CN | disclosed |
| CN-1295995-A | Process for purifying pentafluoroethane | ZHEJIANG PROVICIAL CHEMICAL IN (CN) | 2001-05-23 | — | — | CN | disclosed |
| WO-1998000762-A1 | OPTICAL COATINGS CONTAINING A BINDER AND ONE OR MORE OF POLYHYDROXYFLAVONES, HYDROXYLATED BENZOIC ACID DERIVATIVES AND HYDROXYLATED NAPHTHOIC ACID DERIVATIVES | ZENECA LIMITED (GB) | 1998-01-08 | — | — | WO | disclosed |
| US-4229533-A | CULTIVATING NOCARDIA IN PRESENCE OF LEVCINE, ALPHA-KETOISOCAPROIC ACID OR DERIVATIVES | TAKECA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-10-21 | — | — | US | disclosed |
| US-4228239-A | CULTURE MEDIUM CONTAINS VALINE, ISOBUTYRIC ACID AND/OR THEIR DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1980-10-14 | — | — | US | disclosed |
| US-3943158-A | POLYURETHANE MONOMERS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009532-A1 | Isolated atomoxetine impurity, processes for the preparation of atomoxetine impurities and their use as reference standards | PNMT, HTR3C, TH | AKR1B1 1466/4885GPR84 3251/4885PPARG 2900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.